KCNQ3 antibody, si:ch211-66b9.3 antibody, BFNC2 antibody, EBN2 antibody, KV7.3 antibody, potassium voltage-gated channel subfamily Q member 3 antibody, potassium voltage-gated channel, KQT-like subfamily, member 3 antibody, potassium voltage-gated channel, subfamily Q, member 3 antibody, KCNQ3 antibody, kcnq3 antibody, Kcnq3 antibody
Background
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2).Synonyms: KQT-like 3, Potassium channel subunit alpha KvLQT3, Potassium voltage-gated channel subfamily KQT member 3, Voltage-gated potassium channel subunit Kv7.3