Myeloperoxidase antibody

Catalog No. ABIN953569

Product Details anti-Myeloperoxidase Antibody

Target: Myeloperoxidase (MPO)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myeloperoxidase antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: This antibody is specific for the human Myeloperoxidase (MPO).

Purification: Affinity chromatography

Immunogen: Native human Myeloperoxidase purified from human Neutrophils

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Myeloperoxidase

Target: Myeloperoxidase (MPO)

Alternative Name: Myeloperoxidase (MPO Products)

Synonyms: mKIAA4033 antibody, MPO antibody, LOC100335032 antibody, POX2' antibody, XPOX2' antibody, mpo antibody, mpo-A antibody, pmr-1 antibody, pmr1 antibody, pox2 antibody, xpox2 antibody, myeloperoxidase antibody, myeloperoxidase L homeolog antibody, MPO antibody, Mpo antibody, LOC100335032 antibody, mpo.L antibody

Background: Myeloperoxidase (MPO) is a 150KDa lysosomal hemoprotein located in the azurophilic granules of neutrophils and monocytes. MPO is a dimeric protein and each dimer contains a two variable ~60-kD heavy unit and a two12-kD light subunit. MPO is responsible for the microbicidal activity of neutrophils and monocytes against a wide range of organisms. MPO exerts its activity through the production of the cytotoxic compound hypochlorous acid (HOCl) and through generation of tyrosyl radicals on invading organisms.Synonyms: MPO

Gene ID: 4353

NCBI Accession: NP_000241

Pathways: Chromatin Binding