NFATC4 antibody (C-Term)

Catalog No. ABIN953689

Product Details anti-NFATC4 Antibody

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This NFATC4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-SGFPAPPGEE PPA

Specificity: This antibody is expected to recognise isoform 2 (NP_004545.2), Isoform 3 (NP_001185894.1), Isofrom 4 (NP_001185895.1) and Isofrom 5 (NP_001185896.1).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Pig.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_004545.2, NP_001185894.1, NP_001185895.1, NP_001185896.1. Genename: NFATC4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NFATC4

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Alternative Name: NFATc4 / NFAT3 (NFATC4 Products)

Synonyms: si:dkeyp-66d1.4 antibody, NFATC4 antibody, 3110041H08Rik antibody, AW107667 antibody, AW546455 antibody, Nfat3 antibody, NF-ATc4 antibody, NFAT3 antibody, nuclear factor of activated T-cells 4 antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 antibody, NFATC4 antibody, nfatc4 antibody, Nfatc4 antibody

Background: The protein is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a pre-existing cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4.Synonyms: NF-ATc4, Nuclear factor of activated T-cells, cytoplasmic 4

Gene ID: 4776

NCBI Accession: NP_001129494

Pathways: RTK Signaling, WNT Signaling