PDE3B antibody (Middle Region)

Catalog No. ABIN954064

This Rabbit Polyclonal antibody specifically detects PDE3B in WB, FACS, IF and EIA. It exhibits reactivity toward Human.

Quick Overview for PDE3B antibody (Middle Region) (ABIN954064)

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE3B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-PDE3B Antibody

Binding Specificity: AA 407-435, Middle Region

Specificity: This antibody recognizes Human PDE3B (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 407-435 amino acids from the Central region of Human PDE3B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PDE3B

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Alternative Name: PDE3B

Background: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes, PDE3B may play a role in fat metabolism.Synonyms: 5'-cyclic phosphodiesterase B, CGI-PDE B, CGIP, CGIP1, CGIPDE1, Cyclic GMP-inhibited phosphodiesterase B, HcGIP1, Phosphodiesterase 3B, Phosphodiesterase-3B cGMP-inhibited, cGMP-inhibited 3'

Molecular Weight: 124333 Da

Gene ID: 5140

NCBI Accession: NP_000913

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process