UGT8 antibody (Internal Region)

Catalog No. ABIN955445

Product Details anti-UGT8 Antibody

Target: UGT8 (UDP Glycosyltransferase 8 (UGT8))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This UGT8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-NGKYKRNGHI K Remarks: Reported variants represent identical protein: NP_001121646.1, NP_003351.2.

Specificity: Recognizes UGT8

Cross-Reactivity (Details): Species reactivity (expected):Rat, Dog, Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_003351.2. Genename: UGT8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for UGT8

Target: UGT8 (UDP Glycosyltransferase 8 (UGT8))

Alternative Name: UGT8 / UGT4 (UGT8 Products)

Synonyms: Xlcgt antibody, cgt antibody, ugt4 antibody, AI850488 antibody, AW455908 antibody, Cgt antibody, Ugt8 antibody, mCerGT antibody, CGT antibody, UGT4 antibody, Ugt8a antibody, UDP glycosyltransferase 8 antibody, UDP galactosyltransferase 8A antibody, UGT8 antibody, ugt8 antibody, Ugt8a antibody, Ugt8 antibody

Background: May serve as a flippase as well as a glucosyltransferase that transfers glucose to ceramide. It Catalzes, UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis, first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates.Synonyms: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, CGT, Ceramide UDP-galactosyltransferase, Cerebroside synthase, UDP-galactose-ceramide galactosyltransferase

Gene ID: 7368

NCBI Accession: NP_003351

Pathways: Cell-Cell Junction Organization