KRT16 antibody

Catalog No. ABIN959467

Product Details anti-KRT16 Antibody

Target: KRT16 (Keratin 16 (KRT16))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT16 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Reacts against keratin 16, which is specifically found in hyperproliferative squamous epithelium such as psoriatic lesions and squamous cell carcinomas, e.g. of the lung. It is expressed in suprabasal keratinocytes of wounded epidermis, a situation of high cell turnover. Reactivity is negative in, e.g. normal skin, breast and lung tissue and non-invasive breast carcinoma. However, 10 % of the invasive breast carcinomas tested were diffusely or focally positive with this antibody.

Purification: Purified

Immunogen: Synthetic peptide corresponding to an amino acid sequence of the carboxyl terminus of human keratin 16

Type of Immunogen: Synthetic peptide

Clone: LL025

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-Fr (1:25 - 1:50), WB

Usage: For immunohistochemistry on paraffin embedded tissue sections, high pressure retreival at  pH 8.0 is recommended.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Target Details for KRT16

Target: KRT16 (Keratin 16 (KRT16))

Alternative Name: KRT16 / CK16 / Cytokeratin 16 (KRT16 Products)

Synonyms: CK16 antibody, FNEPPK antibody, K16 antibody, K1CP antibody, KRT16A antibody, NEPPK antibody, AI324768 antibody, Krt1-16 antibody, Ka16 antibody, KRT16 antibody, Krt16 antibody, keratin 16 antibody, keratin 16, type I S homeolog antibody, keratin, type I cytoskeletal 16 antibody, KRT16 antibody, Krt16 antibody, krt16.S antibody, LOC101108147 antibody, LOC100714013 antibody

Background: Name/Gene ID: KRT16

Synonyms: KRT16, CK16, Cytokeratin 16, Cytokeratin-16, FNEPPK, K1CP, Keratin-16, Keratin 16, NEPPK, CK-16, K16, KRT16A

Gene ID: 3868