Melanoma Associated Antigen antibody

Catalog No. ABIN959526

Product Details anti-Melanoma Associated Antigen Antibody

Target: Melanoma Associated Antigen (MAGE)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Melanoma Associated Antigen antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Eacts with Melanoma Associated Antigen, a glycoprotein of 100 + 7 kDa. Melanoma associated antigen (MAA) is dispersed in the cytoplasma of melanoma cells, and is more concentrated inside vacuoles and sometimes on the melanosomes. Occasionally the antigen is seen on the cell surface. The antigen is actively shed from living cells. Melanoma Associated Antigen 100 + 7 kDa is present in melanomas, clear cells sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes. Except for one case of non Hodgkin's lymphoma in which macrophages were positive, the antigen has not been detected with other tumors or tissues observed.The antibody reacts with melanomas, clear cell sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes.

Purification: Purified

Immunogen: smooth membrane fraction of a lymph node metastasis of melanoma

Clone: NKI-beteb

Isotype: IgG2b

Application Details

Application Notes: Approved: IHC, IHC-Fr

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Target Details for Melanoma Associated Antigen

Target: Melanoma Associated Antigen (MAGE)

Alternative Name: Melanoma-Associated Antigen (MAGE Products)

Synonyms: KIAA1641 antibody, ankyrin repeat domain 36B antibody, ANKRD36B antibody