Caspase 8 antibody (AA 217-222) (Biotin)

Catalog No. ABIN959600

The Mouse Monoclonal anti-Caspase 8 antibody has been validated for ELISA. It is suitable to detect Caspase 8 in samples from Human and Monkey.

Quick Overview for Caspase 8 antibody (AA 217-222) (Biotin) (ABIN959600)

Target: Caspase 8 (CASP8)

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is conjugated to Biotin

Application: ELISA

Clone: 90A992

Product Details anti-Caspase 8 Antibody (Biotin)

Binding Specificity: AA 217-222

Specificity: This can be used for detection of the pro-form of Caspase-8.

Purification: Protein G purified

Immunogen: A synthetic peptide corresponding to amino acids 217-222 (SESQTC) of human Caspase-8.

Type of Immunogen: Synthetic peptide

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C, stable for 6 months. DO NOT FREEZE.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8 / Caspase 8

Background: Name/Gene ID: CASP8
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein

Gene ID: 841

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades