Ectodysplasin A2 Receptor antibody

Catalog No. ABIN959863

Product Details anti-Ectodysplasin A2 Receptor Antibody

Target: Ectodysplasin A2 Receptor (EDA2R)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A2 Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Detects human X-linked ectodermal dysplasia receptor (XEDAR), a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist, XEDAR-s and XEDAR-L, produced by alternative splicing.

Purification: Purified

Immunogen: Recombinant human XEDAR.

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (2.5 μg/mL), WB (0.5 - 2 μg/mL)

Usage: Western Blot: Detects a band of approximately 33kD in 293 cell lysates.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for Ectodysplasin A2 Receptor

Target: Ectodysplasin A2 Receptor (EDA2R)

Alternative Name: EDA2R / XEDAR (EDA2R Products)

Synonyms: EDA-A2R antibody, EDAA2R antibody, TNFRSF27 antibody, XEDAR antibody, 9430060M22Rik antibody, Xedar antibody, RGD1564025 antibody, ectodysplasin A2 receptor antibody, EDA2R antibody, Eda2r antibody

Background: Name/Gene ID: EDA2R

Synonyms: EDA2R, EDA-A2R, EDAA2R, Ectodysplasin A2 receptor, TNFRSF27, XEDAR, EDA-A2 receptor, EDAR2

Gene ID: 60401

UniProt: Q9HAV5