AAT antibody

Catalog No. ABIN965493

Product Details

Target: AAT

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human AAT expressed in E. Coli.

Clone: 2B12

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References

Emmerich: "[Rare thrombophilic states]." in: La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne, Vol. 29, Issue 6, pp. 482-5, (2008) (PubMed).

Target Details

Target: AAT

Synonyms: A1A antibody, A1AT antibody, AAT antibody, PI antibody, PI1 antibody, PRO2275 antibody, alpha1AT antibody, serpin family A member 1 antibody, SERPINA1 antibody

Background: AAT, also known as SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.
Synonyms: PI, A1A, AAT, PI1, A1AT, SERPINA1

Molecular Weight: 47kDa

Gene ID: 5265