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AKT2 antibody

AKT2 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN965531
  • Target See all AKT2 Antibodies
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    Reactivity
    • 187
    • 103
    • 68
    • 16
    • 15
    • 13
    • 13
    • 13
    • 11
    • 10
    • 10
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 166
    • 28
    • 5
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 167
    • 34
    Polyclonal
    Conjugate
    • 97
    • 17
    • 16
    • 11
    • 9
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This AKT2 antibody is un-conjugated
    Application
    • 171
    • 109
    • 73
    • 38
    • 28
    • 27
    • 26
    • 20
    • 19
    • 10
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    Akt2 (Ab-474) antibody detects endogenous levels of total Akt2 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    The antiserum was produced against synthesized non-phosphopeptide derived from human Akt2 around the phosphorylation site of serine 474 (Q-F-SP-Y-S).
    Top Product
    Discover our top product AKT2 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Sun, Paciga, Feldman, Yuan, Coppola, Lu, Shelley, Nicosia, Cheng: "Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K." in: Cancer research, Vol. 61, Issue 16, pp. 5985-91, (2001) (PubMed).

    Yuan, Sun, Feldman, Wang, Ma, Jiang, Coppola, Nicosia, Cheng: "Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer." in: Oncogene, Vol. 19, Issue 19, pp. 2324-30, (2000) (PubMed).

    Meier, Alessi, Cron, Andjelković, Hemmings: "Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta." in: The Journal of biological chemistry, Vol. 272, Issue 48, pp. 30491-7, (1997) (PubMed).

  • Target
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    Alternative Name
    AKT2 (AKT2 Products)
    Synonyms
    AKT2 antibody, pkbb antibody, pkbbeta antibody, pkbss antibody, prkbb antibody, rac-beta antibody, v-akt2 antibody, 2410016A19Rik antibody, AW554154 antibody, PKB antibody, PKBbeta antibody, HIHGHH antibody, PKBB antibody, PKBBETA antibody, PRKBB antibody, RAC-BETA antibody, cb945 antibody, akt2-a antibody, AKT serine/threonine kinase 2 antibody, v-akt murine thymoma viral oncogene homolog 2 antibody, thymoma viral proto-oncogene 2 antibody, v-akt murine thymoma viral oncogene homolog 2 L homeolog antibody, AKT2 antibody, akt2 antibody, Akt2 antibody, akt2.L antibody
    Pathways
    PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling
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