CD57 antibody
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- Target See all CD57 (B3GAT1) Antibodies
- CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD57 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- This antibody reacts with a 110 kD human cell surface glycoprotein known as HNK-1. This CD marker recognizes peripheral blood lymphocyte subsets and natural killer (NK) cells. Many cells which co-express CD57 and CD8 antigens are a subset of suppressor/cytotoxic T-cells. These antibodies recognize neuroendocrine cells and their tumors. CD57 antigens are not expressed on erythrocytes or platelets.
- Purification
- Purified.
- Immunogen
- Human peripheral blood mononuclear cells.
- Clone
- B321 (NK-1)
- Isotype
- IgM kappa
- Top Product
- Discover our top product B3GAT1 Primary Antibody
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- Application Notes
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Immunofluorescence: 5-20 ug/mL.
Flow cytometry: 1-5 ug/10^6 cells.
Immunohistochemistry: 5-20 ug/mL on frozen sections and formalin-fixed paraffin-embedded tissue sections using avidin-biotin system.
This product was not quality controlled in flow cytometry.
Staining Procedure: This antibody can be used on frozen cryostat sections as well as formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation is buffered formalin can destroy the epitope. The antibody may be used at a dilution of 5-20 ug/mL in IHC. For consistent and reproducible results on formalin-fixed, paraffin-embedded sections, a high temperature antigen unmasking technique is required (see instructions below). Antibody - Comment
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Cellular Localization: cell membrane.
Recommended Positive Control: Human tonsil, Lymph Node. Natural killer Granulocytess are located mainly in germinal centers. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.4 mg/ml.
- Buffer
- 50 mM Sodium Borate, 150 mM Sodium Chloride, 20% Glycerol, pH 8.0
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))
- Alternative Name
- CD57,HNK-1 (B3GAT1 Products)
- Synonyms
- CD57 antibody, GLCATP antibody, GLCUATP antibody, HNK1 antibody, LEU7 antibody, NK-1 antibody, NK1 antibody, 0710007K08Rik antibody, AI846286 antibody, GlcAT-P antibody, Glcatp antibody, Hnk1 antibody, Hnk-1 antibody, b3gat1 antibody, si:dkey-22o20.1 antibody, cd57 antibody, glcatp antibody, glcuatp antibody, hnk-1 antibody, hnk1 antibody, leu7 antibody, nk-1 antibody, nk1 antibody, beta-1,3-glucuronyltransferase 1 antibody, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) antibody, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a antibody, beta-1,3-glucuronyltransferase 1 L homeolog antibody, B3GAT1 antibody, B3gat1 antibody, b3gat1a antibody, b3gat1.L antibody
- Molecular Weight
- 110 kDa
- Gene ID
- 27087
- Pathways
- Glycosaminoglycan Metabolic Process
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