P-Cadherin antibody (AA 612-626)
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- Target See all P-Cadherin (CDH3) Antibodies
- P-Cadherin (CDH3)
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Binding Specificity
- AA 612-626
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Reactivity
- Human
- Host
- Please inquire
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Clonality
- Polyclonal
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Conjugate
- This P-Cadherin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Immunogen
- A synthetic peptide corresponding to a sequence at the middle region of human P-Cadherin (612-626 aa), different from the mouse and rat sequence by one amino acid.
- Top Product
- Discover our top product CDH3 Primary Antibody
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- Application Notes
- WB: The detection limit for P-Cadherin is approximately 2.5ng/lane under non-reducing and reducing conditions.
- Restrictions
- For Research Use only
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- Reconstitution
- 0.2ml of distilled water will yield a concentration of 500µg/ml.
- Buffer
- Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Storage
- -20 °C
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The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species." in: Genomics, Vol. 14, Issue 2, pp. 488-90, (1992) (PubMed).
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The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species." in: Genomics, Vol. 14, Issue 2, pp. 488-90, (1992) (PubMed).
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- Target
- P-Cadherin (CDH3)
- Alternative Name
- P-Cadherin (CDH3 Products)
- Synonyms
- CDH3 antibody, Cadherin-3 antibody, AI385538 antibody, Cadp antibody, Cdhp antibody, P-cadherin antibody, Pcad antibody, CDHP antibody, HJMD antibody, PCAD antibody, E-Cad antibody, E-cadherin antibody, EP-cadherin antibody, XTCAD-1 antibody, c-cadherin antibody, cadherin-1 antibody, cdh1 antibody, cdh1-b antibody, cdh3 antibody, cdhc-A antibody, cdhp antibody, hjmd antibody, l-cam antibody, lcam antibody, pcad antibody, uvo antibody, uvomorulin antibody, xb-cad antibody, xcdh1 antibody, CDH15 antibody, K-CAM antibody, cadherin 3 antibody, cadherin 3 L homeolog antibody, Cadherin-3 antibody, CDH3 antibody, Cdh3 antibody, cdh3.L antibody, cdh-3 antibody
- Background
- Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
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