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p53 antibody

There are 3+ publications for this product available. The Rabbit Polyclonal anti-p53 antibody is suitable to detect p53 in samples from Human. It has been validated for IHC.
Catalog No. ABIN966758
$411.13
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 7 Business Days

Quick Overview for p53 antibody (ABIN966758)

Target

See all p53 (TP53) Antibodies
p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity

  • 1053
  • 341
  • 270
  • 140
  • 75
  • 74
  • 54
  • 37
  • 11
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Human

Host

  • 788
  • 293
  • 3
  • 3
  • 2
  • 2
Rabbit

Clonality

  • 578
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Polyclonal

Conjugate

  • 555
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  • 2
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  • 1
This p53 antibody is un-conjugated

Application

  • 823
  • 343
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  • 171
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  • 64
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Immunohistochemistry (IHC)
  • Specificity

    P53 (Ab-15) antibody detects endogenous levels of total p53 protein.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Immunogen

    The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine15 (P-L-SP-Q-E).
  • Application Notes

    WB: 1:500~1:1000
    IHC: 1:50~1:100.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    100ug/100ul.

    Buffer

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C
  • Lin, Chao, Saito, Mazur, Murphy, Appella, Xu: "p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression." in: Nature cell biology, Vol. 7, Issue 2, pp. 165-71, (2005) (PubMed).

    Vega, Sevilla, Lazo: "p53 Stabilization and accumulation induced by human vaccinia-related kinase 1." in: Molecular and cellular biology, Vol. 24, Issue 23, pp. 10366-80, (2004) (PubMed).

    Li, Zhang, Sejas, Bagby, Pang: "Hypoxia-induced nucleophosmin protects cell death through inhibition of p53." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 41275-9, (2004) (PubMed).

  • Target

    p53 (TP53) (Tumor Protein P53 (TP53))

    Alternative Name

    P53

    Pathways

    p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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