TDGF1 antibody

Catalog No. ABIN967164

Cited in 1 publication. The Mouse Monoclonal anti-TDGF1 antibody (Clone 3A6) (ABIN967164) specifically detects TDGF1 in ELISA and WB. The antibody is reactive with Human samples.

Quick Overview for TDGF1 antibody (ABIN967164)

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TDGF1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: 3A6

Product Details anti-TDGF1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of TEC expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-TDGF1 antibody (ABIN967164)

Yang, Ghiotto, Barbarat, Olive: "The role of Tec protein-tyrosine kinase in T cell signaling." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 607-17, (1999) (PubMed).

Target Details for TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Alternative Name: TDGF1

Background: TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Synonyms: CR, CRGF, CRIPTO, TDGF1

Molecular Weight: 21kDa

Gene ID: 6997

Pathways: EGFR Signaling Pathway