Tec Protein Tyrosine Kinase (TEC) antibody

Catalog No. ABIN967165

This Mouse Monoclonal antibody specifically detects Tec Protein Tyrosine Kinase in WB and ELISA. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for Tec Protein Tyrosine Kinase (TEC) antibody (ABIN967165)

Target: Tec Protein Tyrosine Kinase (TEC)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3A5

Product Details

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of TEC expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References

Yang, Ghiotto, Barbarat, Olive: "The role of Tec protein-tyrosine kinase in T cell signaling." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 607-17, (1999) (PubMed).

Target Details

Target: Tec Protein Tyrosine Kinase (TEC)

Alternative Name: TEC

Background: TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Synonyms: PSCTK4

Molecular Weight: 74kDa

Gene ID: 7006

Pathways: Fc-epsilon Receptor Signaling Pathway