LTA antibody (AA 73-88)

Catalog No. ABIN967194

Product Details anti-LTA Antibody

Target: LTA (Lymphotoxin-alpha (LTA))

Binding Specificity: AA 73-88

Reactivity: Human

Host: Please inquire

Clonality: Polyclonal

Conjugate: This LTA antibody is un-conjugated

Application: Western Blotting (WB)

Immunogen: A synthetic peptide corresponding to a sequence at the middle region of human TNF (73-88 aa), different from the mouse sequence by one amino acid.

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Preservative: Thimerosal (Merthiolate), Sodium azide

Storage: -20 °C

Target Details for LTA

Target: LTA (Lymphotoxin-alpha (LTA))

Alternative Name: TNFbeta (LTA Products)

Synonyms: LT antibody, TNFB antibody, TNFSF1 antibody, LT-[a] antibody, LT-alpha antibody, LT[a] antibody, LTalpha antibody, Ltx antibody, TNF-beta antibody, Tnfb antibody, Tnfsf1b antibody, hlb382 antibody, lymphotoxin alpha antibody, lymphotoxin A antibody, LTA antibody, Lta antibody

Target Type: Chemical

Background: Lymphotoxin (previously known as tumor necrosis factor-beta) is a lymphokine cytokine.It is a protein that is produced by Th1 type T-cells and induces vascular endothelial cells to change their surface adhesion molecules to allow phagocytic cells to bind to them. Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs. Nedwin et al. (1985) found that TNFA and TNFB are closely linked on chromosome 6. Study of hybrid cells made with rearranged human chromosome 6 showed that both TNFA and TNFB map to the 6p23-q12 segment.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process