CAMK2A antibody (Calcium/calmodulin-Dependent Protein Kinase II alpha) (AA 448-460)

Details for Product anti-CAMK2A Antibody No. ABIN968457, Supplier: Log in to see
Antigen
  • camk2
  • camk2b
  • zgc:112538
  • zgc:123320
  • CAMKA
  • CaMKII
  • R74975
  • mKIAA0968
  • PK2CDD
  • PKCCD
  • calcium/calmodulin dependent protein kinase II alpha
  • calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog
  • calcium/calmodulin-dependent protein kinase II alpha
  • CAMK2A
  • camk2a.S
  • camk2a
  • Camk2a
Alternatives
anti-Human CAMK2A antibody for Western Blotting
137 anti-Human CAMK2A antibody for Western Blotting
94 anti-Mouse (Murine) CAMK2A antibody for Western Blotting
88 anti-Rat (Rattus) CAMK2A antibody for Western Blotting
9 anti-Xenopus laevis CAMK2A antibody for Western Blotting
62 anti-Human CAMK2A antibody for ELISA
6 anti-Chicken CAMK2A antibody for Western Blotting
28 anti-Cow (Bovine) CAMK2A antibody for Western Blotting
21 anti-Cow (Bovine) CAMK2A antibody for ELISA
19 anti-Cow (Bovine) CAMK2A antibody for Immunofluorescence
21 anti-Cow (Bovine) CAMK2A antibody for Immunohistochemistry
18 anti-Cow (Bovine) CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
19 anti-Cow (Bovine) CAMK2A antibody for Immunoprecipitation
20 anti-Cow (Bovine) CAMK2A antibody for Radioimmunoassay
45 anti-Mouse (Murine) CAMK2A antibody for ELISA
1 anti-Mouse (Murine) CAMK2A antibody for Immunocytochemistry
30 anti-Mouse (Murine) CAMK2A antibody for Immunofluorescence
29 anti-Mouse (Murine) CAMK2A antibody for Immunohistochemistry
34 anti-Mouse (Murine) CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
22 anti-Mouse (Murine) CAMK2A antibody for Immunoprecipitation
21 anti-Mouse (Murine) CAMK2A antibody for Radioimmunoassay
36 anti-Rat (Rattus) CAMK2A antibody for ELISA
4 anti-Rat (Rattus) CAMK2A antibody for Immunocytochemistry
35 anti-Rat (Rattus) CAMK2A antibody for Immunofluorescence
32 anti-Rat (Rattus) CAMK2A antibody for Immunohistochemistry
35 anti-Rat (Rattus) CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
27 anti-Rat (Rattus) CAMK2A antibody for Immunoprecipitation
23 anti-Rat (Rattus) CAMK2A antibody for Radioimmunoassay
2 anti-Dog (Canine) CAMK2A antibody for Enzyme Immunoassay
9 anti-Dog (Canine) CAMK2A antibody for Western Blotting
1 anti-Chicken CAMK2A antibody for Enzyme Immunoassay
7 anti-Human CAMK2A antibody for Enzyme Immunoassay
3 anti-Mouse (Murine) CAMK2A antibody for Enzyme Immunoassay
2 anti-Pig (Porcine) CAMK2A antibody for Enzyme Immunoassay
4 anti-Pig (Porcine) CAMK2A antibody for Western Blotting
2 anti-Rabbit CAMK2A antibody for Enzyme Immunoassay
5 anti-Rabbit CAMK2A antibody for Western Blotting
4 anti-Rat (Rattus) CAMK2A antibody for Enzyme Immunoassay
2 anti-Zebrafish (Danio rerio) CAMK2A antibody for Enzyme Immunoassay
3 anti-Zebrafish (Danio rerio) CAMK2A antibody for Western Blotting
1 anti-Human CAMK2A antibody for Immunocytochemistry
37 anti-Human CAMK2A antibody for Immunofluorescence
48 anti-Human CAMK2A antibody for Immunohistochemistry
51 anti-Human CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
20 anti-Human CAMK2A antibody for Immunoprecipitation
2 anti-Guinea Pig CAMK2A antibody for Western Blotting
2 anti-Hamster CAMK2A antibody for Western Blotting
4 anti-Human CAMK2A antibody for Immunohistochemistry (Frozen Sections)
2 anti-Human CAMK2A antibody for Dot Blot
2 anti-Mouse (Murine) CAMK2A antibody for Dot Blot
2 anti-Rat (Rattus) CAMK2A antibody for Dot Blot
2 anti-Xenopus laevis CAMK2A antibody for Dot Blot
1 anti-Cow (Bovine) CAMK2A antibody for Dot Blot
1 anti-Chicken CAMK2A antibody for Dot Blot
2 anti-Frog CAMK2A antibody for Enzyme Immunoassay
1 anti-Frog CAMK2A antibody for Immunofluorescence
1 anti-Frog CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
2 anti-Frog CAMK2A antibody for Western Blotting
1 anti-Pig (Porcine) CAMK2A antibody for Immunofluorescence
2 anti-Pig (Porcine) CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
1 anti-Rabbit CAMK2A antibody for Immunofluorescence
2 anti-Rabbit CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
1 anti-Zebrafish (Danio rerio) CAMK2A antibody for Immunofluorescence
1 anti-Zebrafish (Danio rerio) CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
1 anti-Xenopus laevis CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
2 anti-Pig (Porcine) CAMK2A antibody for ELISA
1 anti-Rabbit CAMK2A antibody for ELISA
3 anti-Dog (Canine) CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
1 anti-Cow (Bovine) CAMK2A antibody for Immunohistochemistry (Frozen Sections)
1 anti-Cow (Bovine) CAMK2A antibody for Enzyme Immunoassay
17 anti-Human CAMK2A antibody for Radioimmunoassay
3 anti-Mouse (Murine) CAMK2A antibody for Immunohistochemistry (Frozen Sections)
4 anti-Rat (Rattus) CAMK2A antibody for Immunohistochemistry (Frozen Sections)
2 anti-Human CAMK2A antibody for Proximity Ligation Assay
4 anti-Dog (Canine) CAMK2A antibody for ELISA
2 anti-Dog (Canine) CAMK2A antibody for BioImaging
3 anti-Dog (Canine) CAMK2A antibody for Immunofluorescence
4 anti-Dog (Canine) CAMK2A antibody for Immunohistochemistry
2 anti-Human CAMK2A antibody for BioImaging
2 anti-Mouse (Murine) CAMK2A antibody for BioImaging
2 anti-Rat (Rattus) CAMK2A antibody for BioImaging
1 anti-Pig (Porcine) CAMK2A antibody for Immunohistochemistry
2 anti-Monkey CAMK2A antibody for ELISA
2 anti-Monkey CAMK2A antibody for Western Blotting
1 anti-Monkey CAMK2A antibody for Immunohistochemistry
1 anti-Xenopus laevis CAMK2A antibody for ELISA
1 anti-Xenopus laevis CAMK2A antibody for Immunohistochemistry
1 anti-Horse (Equine) CAMK2A antibody for Western Blotting
1 anti-Rat (Rattus) CAMK2A antibody for Immunofluorescence (fixed cells)
1 anti-Chicken CAMK2A antibody for ELISA
2 anti-Xenopus laevis CAMK2A antibody for Immunohistochemistry (Frozen Sections)
1 anti-Bat CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
1 anti-Bat CAMK2A antibody for ELISA
1 anti-Bat CAMK2A antibody for Western Blotting
1 anti-Horse (Equine) CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
1 anti-Horse (Equine) CAMK2A antibody for ELISA
1 anti-Monkey CAMK2A antibody for Immunohistochemistry (Paraffin-embedded Sections)
1 anti-Fish CAMK2A antibody for Immunoprecipitation
1 anti-Fish CAMK2A antibody for Immunohistochemistry
1 anti-Fish CAMK2A antibody for ELISA
1 anti-Fish CAMK2A antibody for Western Blotting
1 anti-Sheep (Ovine) CAMK2A antibody for Immunoprecipitation
1 anti-Sheep (Ovine) CAMK2A antibody for Immunohistochemistry
1 anti-Sheep (Ovine) CAMK2A antibody for ELISA
1 anti-Sheep (Ovine) CAMK2A antibody for Western Blotting
1 anti-Orang-Utan (Pongo abelii) CAMK2A antibody for Enzyme Immunoassay
1 anti-Orang-Utan (Pongo abelii) CAMK2A antibody for Western Blotting
Epitope
AA 448-460
38
32
12
10
9
7
6
6
5
5
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
145
98
91
28
11
8
6
5
4
3
2
2
2
2
1
1
1
1
1
Host
Mouse
118
53
18
Clonality (Clone)
Monoclonal ()
Conjugate
This CAMK2A antibody is un-conjugated
6
6
6
6
6
5
1
1
1
1
1
1
1
1
1
1
1
Application
BioImaging (BI), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
180
87
58
53
43
26
23
7
5
4
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Rat CaM Kinase IIalpha aa. 448-460
Clone 45-CaM Kinase II
Isotype IgG1
Cross-Reactivity Mouse (Murine), Human, Dog (Canine)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Name CaM Kinase II (CAMK2A Antibody Abstract)
Background Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) is a multifunctional Ser/Thr kinase that regulates a number of cellular functions in response to increased intracellular Ca2+. CaM kinase II is widely distributed, but is predominantly expressed in brain. It is involved in the regulation of neuronal functions such as neurotransmitter synthesis, neurotransmitter release, long-term potentiation, and formation of spatial learning. Neuronal CaM kinase II contains heteromers of two major subunits, alpha and beta, at a ratio of 2:1 and homomers of alpha subunits. Each subunit has N-terminal ATP-binding and catalytic/regulatory domains and a C-terminal association domain. The regulatory domain consists of the autoinhibitory and calmodulin-binding sites. Assembly of the association domains of multiple subunits positions the regulatory domains for intersubunit autophosphorylation. After binding Ca2+/calmodulin, CaM kinase II undergoes rapid autophosphorylation of the alpha and beta subunits, which results in a substantial increase in its affinity for Ca2+/calmodulin.
Synonyms: Ca2+/calmodulin-dependent protein kinase II
Molecular Weight 52 kDa
Pathways WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
Comment

Related Products: ABIN967389, ABIN968545
Restrictions For Research Use only
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.
Supplier Images
Western Blotting (WB) image for anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 448-460) antibody (ABIN968457) Western blot analysis of CaM Kinase II on a rat cerebrum lysate (First Panel). Lane 1...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 448-460) antibody (ABIN968457) Immunohistochemical staining of CaM Kinase II on rat brain (center panel). Formalin-f...
Immunofluorescence (IF) image for anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 448-460) antibody (ABIN968457) Immunofluorescence staining of SK-N-SH cells (Human neuroblastoma, ATCC HTB-11) (Seco...
Product cited in: Fallon, Moreau, Croft, Labib, Gu, Fon: "Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 486-91, 2002 (PubMed).

Zong, Ren, Young, Pypaert, Mu, Birnbaum, Shulman: "AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 25, pp. 15983-7, 2002 (PubMed).

Brocke, Chiang, Wagner, Schulman: "Functional implications of the subunit composition of neuronal CaM kinase II." in: The Journal of biological chemistry, Vol. 274, Issue 32, pp. 22713-22, 1999 (PubMed).

Ishida, Fujisawa: "Stabilization of calmodulin-dependent protein kinase II through the autoinhibitory domain." in: The Journal of biological chemistry, Vol. 270, Issue 5, pp. 2163-70, 1995 (PubMed).

Hanson, Schulman: "Neuronal Ca2+/calmodulin-dependent protein kinases." in: Annual review of biochemistry, Vol. 61, pp. 559-601, 1992 (PubMed).

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