CDK5 antibody

Catalog No. ABIN969041

The Mouse Monoclonal anti-CDK5 antibody has been validated for WB, ELISA, IHC, FACS and ICC. It is suitable to detect CDK5 in samples from Human, Rat and Monkey. There are 2+ publications available.

Quick Overview for CDK5 antibody (ABIN969041)

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Reactivity: Human, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 4E4

Product Details anti-CDK5 Antibody

Purpose: CDK5 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CDK5 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CDK5 antibody (ABIN969041)

Choi, Lee, Park, Sung, Lee, Shin, Ryu, Kim: "Single-nucleotide polymorphisms in the promoter of the CDK5 gene and lung cancer risk in a Korean population." in: Journal of human genetics, Vol. 54, Issue 5, pp. 298-303, (2009) (PubMed).

Zhang, Herrup: "Cdk5 and the non-catalytic arrest of the neuronal cell cycle." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3487-90, (2008) (PubMed).

Target Details for CDK5

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Alternative Name: CDK5

Background: Function: Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.

Molecular Weight: 35 kDa

UniProt: Q00535

Pathways: Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis