KSHV ORF8 antibody
Reactivity: Human
ELISA, WB
Host: Mouse
Polyclonal
unconjugated
1 image
(1 reference)-
- Target
- KSHV ORF8
- Reactivity
- Human
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Host
- Mouse
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
- Application
- ELISA, Western Blotting (WB)
- Immunogen
- Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8.
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit anti-serum.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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: "Human herpesvirus 8 envelope glycoprotein B mediates cell adhesion via its RGD sequence." in: Journal of virology, Vol. 77, Issue 5, pp. 3131-47, (2003) (PubMed).
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: "Human herpesvirus 8 envelope glycoprotein B mediates cell adhesion via its RGD sequence." in: Journal of virology, Vol. 77, Issue 5, pp. 3131-47, (2003) (PubMed).
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- Target
- KSHV ORF8
- Target Type
- Viral Protein
- Background
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Description: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
Aliases: ORF8
- Gene ID
- 4961501
- HGNC
- 4961501
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