anti-Human FASL antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FASL Antibody (supplied by: Log in to see )

Antigen
Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
  • ALPS1B
  • APT1LG1
  • APTL
  • CD178
  • CD95-L
  • CD95L
  • FASL
  • TNFSF6
  • fasl
  • Fas-L
  • Faslg
  • Tnfsf6
  • gld
  • Apt1Lg1
  • Fasl
  • FASLG
  • zgc:162027
  • Fas ligand
  • Fas ligand L homeolog
  • Fas ligand (TNF superfamily, member 6)
  • FASLG
  • faslg.L
  • Fasl
  • Faslg
  • faslg
Epitope
AA 170-220
26
18
17
15
13
12
9
7
7
6
5
5
5
5
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
437
174
85
36
7
5
5
3
3
2
1
Host
Rabbit
278
170
49
33
32
9
1
Clonality
Polyclonal
Conjugate
This FASL antibody is un-conjugated
47
32
29
14
13
13
10
10
9
9
9
9
9
9
8
7
7
3
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
338
260
127
100
75
70
52
48
29
28
12
12
10
10
9
5
3
2
2
1
1
1
1
1
1
1
Options
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Catalog No. ABIN726410
$ 318.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.813775 ABIN1105940 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
12.813775 ABIN462004 IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0
12.813775 ABIN615525 IHC (p) WB Rabbit Log in to see Polyclonal 0
12.813775 ABIN615086 IHC (p) Rabbit N-Term Log in to see Polyclonal 0
12.813775 ABIN615080 IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0
12.813775 ABIN4310551 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN3043159 IHC (p) WB Rabbit IgG AA 263-281, C-Term Log in to see Polyclonal 7
1 ABIN155064 IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see I-6060 0
1 ABIN574121 IHC (p) WB Rabbit AA 82-145 Log in to see Polyclonal 0
1 ABIN265415 IF IHC (p) WB Rabbit Log in to see Polyclonal 0
1 ABIN1494375 IHC (p) Rabbit N-Term Log in to see Polyclonal 0
1 ABIN1492926 ICC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN2889193 IHC (p) ELISA WB Rabbit IgG AA 101-150 Log in to see Polyclonal 0
1 ABIN726419 IHC (p) WB HRP Rabbit IgG AA 170-220 Log in to see Polyclonal 0
1 ABIN609580 ICC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN465173 IHC (p) Neut ELISA WB Goat Log in to see Polyclonal 0
1 ABIN726412 IHC (p) WB Biotin Rabbit IgG AA 170-220 Log in to see Polyclonal 0
1 ABIN2620711 IHC (p) WB Rabbit IgG AA 263-281 Log in to see Polyclonal 0
1 ABIN1820317 IHC (p) WB Rabbit AA 192-218 Log in to see Polyclonal 0
1 ABIN2852378 IHC (p) Rabbit IgG N-Term Log in to see Polyclonal 0

General

Antigen Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
Epitope AA 170-220
(26), (18), (17), (15), (13), (12), (9), (7), (7), (6), (5), (5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(437), (174), (85), (36), (7), (5), (5), (3), (3), (2), (1)
Host Rabbit
(278), (170), (49), (33), (32), (9), (1)
Clonality
Polyclonal
Conjugate This FASL antibody is un-conjugated
(47), (32), (29), (14), (13), (13), (10), (10), (9), (9), (9), (9), (9), (9), (8), (7), (7), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(338), (260), (127), (100), (75), (70), (52), (48), (29), (28), (12), (12), (10), (10), (9), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-FASL Antibody

Target Details FASL Application Details Handling References for anti-FASL antibody (ABIN726410) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Fas Ligand
Isotype IgG

Target Details FASL

Product Details anti-FASL Antibody Application Details Handling References for anti-FASL antibody (ABIN726410) Images back to top
Antigen
Alternative Name Fas Ligand (FASL Antibody Abstract)
Background

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

Subcellular location: Extracellular

Synonyms: APTL, FASL, CD178, CD95L, ALPS1B, CD95-L, TNFSF6, APT1LG1, Tumor necrosis factor ligand superfamily member 6, Apoptosis antigen ligand, CD95 ligand, Fas antigen ligand, Fas ligand, FASLG

Gene ID 356
UniProt P48023
Pathways Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FASL Antibody Target Details FASL Handling References for anti-FASL antibody (ABIN726410) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-FASL Antibody Target Details FASL Application Details References for anti-FASL antibody (ABIN726410) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-FASL antibody (ABIN726410)

Product Details anti-FASL Antibody Target Details FASL Application Details Handling Images back to top
Product cited in:

Lv, Zheng, Zhou, Jia, Wang, Liu, Zhao, Ji, Li, Cao: "Antiproliferative and Apoptosis-inducing Effect of exo-Protoporphyrin IX based Sonodynamic Therapy on Human Oral Squamous Cell Carcinoma." in: Scientific reports, Vol. 7, pp. 40967, 2017 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Mouse (Murine)).

Wang, Zhang, Yang, Luo, Zhang, Wang: "Lipopolysaccharide-induced expression of FAS ligand in cultured immature boar sertoli cells through the regulation of pro-inflammatory cytokines and miR-187." in: Molecular reproduction and development, 2015 Method employed by authors: Western Blotting (WB)

Song, Li, Shi, Lehmler, Fu, Su, Xia, Song, Song: "Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells." in: Chemical research in toxicology, Vol. 28, Issue 11, pp. 2160-9, 2015 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Human).

Qi, Fu, Wang, Liu, Quan, Kourouma, Yan, Yu, Duan, Yang: "BPA-induced apoptosis of rat Sertoli cells through Fas/FasL and JNKs/p38 MAPK pathways." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 50, pp. 108-16, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Chen, Xie, Xue, Ji, Chang, Ma, Bi: "Characterization of cytotoxicity-related gene expression in response to virulent Marek's disease virus infection in the bursa of Fabricius." in: Research in veterinary science, Vol. 94, Issue 3, pp. 496-503, 2013 Method employed by authors: Western Blotting (WB) (Sample species: Chicken). Further details: Sample: bursa of Fabriciu

Shi, Song, Wang, Wang, Liang, Hu, Yu, Guan, Cheng, Yang: "β-Benzene hexachloride induces apoptosis of rat Sertoli cells through generation of reactive oxygen species and activation of JNKs and FasL." in: Environmental toxicology, Vol. 26, Issue 2, pp. 124-35, 2011 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Shi, Song, Wang, Liang, Hu, Guan, Cheng, Yang: "p,p'-DDE induces apoptosis of rat Sertoli cells via a FasL-dependent pathway." in: Journal of biomedicine & biotechnology, Vol. 2009, pp. 181282, 2009 (Sample species: Rat (Rattus)).

Images

Product Details anti-FASL Antibody Target Details FASL Application Details Handling References for anti-FASL antibody (ABIN726410) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-FasL Polyclo...
Immunohistochemistry (IHC) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Formalin-fixed and paraffin embedded: human rectal carcinoma labeled with Anti-FasL P...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Formalin-fixed and paraffin embedded: human rectal carcinoma labeled with Anti-FasL P...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-FasL Polyclo...
 image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Jurkat lysates probed with Fas Ligand Polyclonal Antibody, Unconjugated at 1:1000 di...
 image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Bone lysates probed with Fas Ligand Polyclonal Antibody, Unconjugated at 1:300 dilut...