anti-Mouse (Murine) BTRC antibody for Western Blotting

Recommended BTRC Antibody (supplied by: Log in to see )

Antigen
beta-Transducin Repeat Containing (BTRC) Antibodies
  • BTRC
  • Beta-TrCP
  • betaTrCP
  • btrcp
  • btrcp1
  • fbw1a
  • fbxw1
  • fbxw1a
  • fwd1
  • btrc
  • beta-TrCP
  • BETA-TRCP
  • FBW1A
  • FBXW1
  • FBXW1A
  • FWD1
  • bTrCP
  • bTrCP1
  • beta-TrCP1
  • btrc-a
  • Beta-Trcp1
  • Fbw1a
  • HOS
  • Slimb
  • b-TrCP
  • mKIAA4123
  • beta-transducin repeat containing E3 ubiquitin protein ligase
  • beta-transducin repeat containing
  • beta-TrCP
  • beta-transducin repeat containing E3 ubiquitin protein ligase S homeolog
  • beta-transducin repeat containing protein
  • BTRC
  • btrc
  • LOC100634006
  • Btrc
  • btrc.S
Epitope
C-Term
14
11
10
8
4
2
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
58
11
10
2
2
2
2
1
1
1
Host
Rabbit
37
21
Clonality
Polyclonal
Conjugate
This BTRC antibody is un-conjugated
3
3
3
2
2
2
Application
Western Blotting (WB)
54
29
27
24
8
6
5
3
1
1
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Available images

Catalog No. ABIN2775273
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0813878 ABIN2775272 WB Rabbit N-Term Log in to see Polyclonal 0
3.0813878 ABIN1871369 IHC WB Rabbit IgG Log in to see Polyclonal 0
3.0813878 ABIN2990079 IF/ICC WB Rabbit IgG Log in to see Polyclonal 0
3.0813878 ABIN3022334 IHC WB Rabbit IgG Log in to see Polyclonal 0
3.0813878 ABIN5963037 WB Rabbit IgG Log in to see Polyclonal 0
3.0813878 ABIN5545131 WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN798672 WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN6260326 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2879841 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2894574 IHC WB Rabbit Log in to see Polyclonal 0

General

Antigen beta-Transducin Repeat Containing (BTRC) Antibodies
Epitope C-Term
(14), (11), (10), (8), (4), (2), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(58), (11), (10), (2), (2), (2), (2), (1), (1), (1)
Host Rabbit
(37), (21)
Clonality
Polyclonal
Conjugate This BTRC antibody is un-conjugated
(3), (3), (3), (2), (2), (2)
Application Western Blotting (WB)
(54), (29), (27), (24), (8), (6), (5), (3), (1), (1)
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Product Details anti-BTRC Antibody

Target Details BTRC Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN973943
Sequence LVEHSGRVFR LQFDEFQIVS SSHDDTILIW DFLNDPAAHA EPPRSPSRTY
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 86%
Characteristics This is a rabbit polyclonal antibody against Btrc. It was validated on Western Blot.
Purification Affinity Purified
Plasmids, Primers & others

Target Details BTRC

Product Details anti-BTRC Antibody Application Details Handling Images back to top
Antigen
Alternative Name Btrc (BTRC Antibody Abstract)
Background Btrc is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It recognizes and binds to phosphorylated target proteins. SCF(BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling. SCF(BTRC) mediates the ubiquitination of NFKBIA, NFKBIB and NFKBIE, the degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. Ubiquitination of NFKBIA occurs at 'Lys-21' and 'Lys-22'. SCF(BTRC) mediates the ubiquitination of phosphorylated NFKB1/nuclear factor NF-kappa-B p105 subunit, ATF4, SMAD3, SMAD4, CDC25A, DLG1, FBXO5 and probably NFKB2. SCF(BTRC) mediates the ubiquitination of phosphorylated SNAI1.
Alias Symbols: Beta-Trcp1, FWD1, Fbw1a, KIAA4123, Slimb, b-TrCP, beta-TrCP, mKIAA4123, HOS
Protein Interaction Partner: ZRANB1, Tpx2, Taz, Per2, Cul1, Skp1a, Reg1, Stat1, Nfe2l2, Per1, Htt, Cops2, Ikbkb, Nkx3-2, Cdc25b, Nfkbia, Gli2,
Protein Size: 605
Molecular Weight 69 kDa
Gene ID 12234
NCBI Accession NM_001037758, NP_001032847
UniProt Q3ULA2
Pathways Cell Division Cycle, Hedgehog Signaling

Application Details

Product Details anti-BTRC Antibody Target Details BTRC Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 605 AA

Restrictions For Research Use only

Handling

Product Details anti-BTRC Antibody Target Details BTRC Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-BTRC Antibody Target Details BTRC Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-beta-Transducin Repeat Containing (BTRC) (C-Term) antibody (ABIN2775273) WB Suggested Anti-Btrc Antibody Titration: 1.0 ug/ml Positive Control: Mouse Panc...