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|Antigen||Complement Factor H (CFH) Antibodies|
|Conjugate||This Complement Factor H antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
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Product Details anti-Complement Factor H AntibodyTarget Details Complement Factor H Application Details Handling Images
|Specificity||Clone OX-24 inhibits the binding of factor H to surface bound C3. This antibody recognizes the Human serum complement protein factor H and a 43-49 kDa truncated form of factor H.|
|Cross-Reactivity (Details)||Species reactivity (tested):Human.|
|Characteristics||Synonyms: CFH, HF, HF1, HF2, H factor 1|
|Purification||Protein G Chromatography.|
|Immunogen||Purified Human complement factor H protein|
Target Details Complement Factor HProduct Details anti-Complement Factor H Antibody Application Details Handling Images back to top
|Background||Factor H (CFH) is a protein with twenty short consensus repeat (SCR) domains. Factor H is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in Factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: CFH, H factor 1, HF, HF1, HF2|
|Pathways||Complement System, Cellular Response to Molecule of Bacterial Origin|
Application DetailsProduct Details anti-Complement Factor H Antibody Target Details Complement Factor H Handling Images back to top
ELISA. Western blot. Immunoprecipitation. Flow Cytometry. Immunohistochemistry on Paraffin Sections: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details Images back to top
|Buffer||PBS containing 0.02 % Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
ImagesProduct Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details Handling back to top