anti-Human Complement Factor H antibody for Immunofluorescence

Recommended Complement Factor H Antibody (supplied by: Log in to see )

Antigen
Complement Factor H (CFH) Antibodies
  • CFH
  • im:7147412
  • si:ch211-207o17.2
  • Mud-1
  • NOM
  • Sas-1
  • Sas1
  • AHUS1
  • AMBP1
  • ARMD4
  • ARMS1
  • CFHL3
  • FH
  • FHL1
  • HF
  • HF1
  • HF2
  • HUS
  • Fh
  • fH
  • complement factor H
  • complement component factor h
  • CFH
  • cfh
  • Cfh
Epitope
AA 751-780, Middle Region
24
18
17
15
11
7
4
3
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
242
35
31
4
4
3
3
2
2
Host
Rabbit
104
104
32
24
2
1
Clonality
Polyclonal
Conjugate
This Complement Factor H antibody is un-conjugated
20
14
6
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
180
151
62
42
37
27
26
21
12
11
10
9
6
5
4
2
1
1
1
1
1
Supplier
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Catalog No. ABIN951646
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.14905 ABIN654896 IF IHC (p) WB Rabbit Ig AA 751-780, Center Log in to see Polyclonal 2
1 ABIN4903257 IF IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN1966875 IF IHC ELISA WB Biotin Rabbit IgG AA 751-780 Log in to see Polyclonal
1 ABIN1964273 IF IHC ELISA WB APC Rabbit IgG AA 751-780 Log in to see Polyclonal
1 ABIN1961894 IF IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 751-780 Log in to see Polyclonal
1 ABIN1970709 IF IHC ELISA WB FITC Rabbit IgG AA 751-780 Log in to see Polyclonal
1 ABIN1973503 IF IHC ELISA WB HRP Rabbit IgG AA 751-780 Log in to see Polyclonal
1 ABIN1975291 IF IHC ELISA WB PE Rabbit IgG AA 751-780 Log in to see Polyclonal
1 ABIN2619178 ELISA IF IHC WB Rabbit IgG AA 751-780 Log in to see Polyclonal
1 ABIN2232270 IF IHC ELISA WB FITC Rabbit IgG AA 751-780, Center, Internal Region Log in to see Polyclonal
1 ABIN2232272 IF IHC ELISA WB PE Rabbit IgG AA 751-780, Center, Internal Region Log in to see Polyclonal
1 ABIN2232273 IF IHC ELISA WB Rabbit IgG AA 751-780, Center, Internal Region Log in to see Polyclonal
1 ABIN2232277 IF IHC ELISA WB APC Rabbit IgG AA 751-780, Center, Internal Region Log in to see Polyclonal
1 ABIN2232276 IF IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 751-780, Center, Internal Region Log in to see Polyclonal
1 ABIN2232278 IF IHC ELISA WB Biotin Rabbit IgG AA 751-780, Center, Internal Region Log in to see Polyclonal
1 ABIN5565315 FACS ICC IF IHC PE Rabbit Log in to see Polyclonal
1 ABIN5565313 FACS ICC IF IHC FITC Rabbit Log in to see Polyclonal
1 ABIN5565312 FACS ICC IF IHC APC Rabbit Log in to see Polyclonal
1 ABIN1173339 ICC IF IHC WB FITC Rabbit IgG Log in to see Polyclonal
1 ABIN1814261 IF IHC (p) WB Rabbit AA 751-780 Log in to see Polyclonal

General

Antigen Complement Factor H (CFH) Antibodies
Epitope AA 751-780, Middle Region
(24), (18), (17), (15), (11), (7), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(242), (35), (31), (4), (4), (3), (3), (2), (2)
Host Rabbit
(104), (104), (32), (24), (2), (1)
Clonality
Polyclonal
Conjugate This Complement Factor H antibody is un-conjugated
(20), (14), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(180), (151), (62), (42), (37), (27), (26), (21), (12), (11), (10), (9), (6), (5), (4), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Complement Factor H Antibody

Target Details Complement Factor H Application Details Handling References for anti-Complement Factor H antibody (ABIN951646) Images
Specificity This antibody reacts to CFH.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH
Isotype Ig

Target Details Complement Factor H

Product Details anti-Complement Factor H Antibody Application Details Handling References for anti-Complement Factor H antibody (ABIN951646) Images back to top
Antigen
Background This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: CFH, H factor 1, HF, HF1, HF2
Molecular Weight 139096 Da
Gene ID 3075
NCBI Accession NP_000177
Research Area Coagulation, Complement Factors
Pathways Complement System, Cellular Response to Molecule of Bacterial Origin

Application Details

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Handling References for anti-Complement Factor H antibody (ABIN951646) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details References for anti-Complement Factor H antibody (ABIN951646) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Complement Factor H antibody (ABIN951646)

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details Handling Images back to top
Background publications

Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: "Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement." in: Infection and immunity, Vol. 78, Issue 11, pp. 4467-76, 2010

Sofat, Casas, Kumari, Talmud, Ireland, Kivimaki, Marmot, Hughes, Thom, Ebrahim, Whittaker, Smeeth, Lawlor, Humphries, Hingorani: "Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals." in: Atherosclerosis, Vol. 213, Issue 1, pp. 184-90, 2010

Davila, Wright, Khor, Sim, Binder, Breunis, Inwald, Nadel, Betts, Carrol, de Groot, Hermans, Hazelzet, Emonts, Lim, Kuijpers, Martinon-Torres, Salas, Zenz, Levin, Hibberd: "Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease." in: Nature genetics, Vol. 42, Issue 9, pp. 772-6, 2010

Images

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details Handling References for anti-Complement Factor H antibody (ABIN951646) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibody (ABIN951646) Confocal immunofluorescent analysis of CFH Antibody (Center) with A549 cell followed ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibody (ABIN951646) CFH antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin em...
Western Blotting (WB) image for anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibody (ABIN951646) CFH Antibody (Center) western blot analysis in K562 cell line lysates (35µg/lane).Thi...