|Antigen||Kallikrein 11 (KLK11) Antibodies|
|Epitope||AA 68-82 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Kallikrein 11 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-Kallikrein 11 AntibodyTarget Details Kallikrein 11 Application Details Handling Images
|Specificity||Recognizes the residues 68-82 [YIVHLGQHNLQKEEG] of the 35 kDa human Hippostasin/KLK11 protein.|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|Immunogen||Synthetic peptide corresponding to aa 68-82 of Human Kallikrein-11.|
Target Details Kallikrein 11Product Details anti-Kallikrein 11 Antibody Application Details Handling Images back to top
|Alternative Name||KLK11 / Kallikrein-11 (KLK11 Antibody Abstract)|
|Background||Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of hK11 were found in 70 % of women with ovarian cancer and in 60 % of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.Synonyms: Hippostasin, PRSS20, Serine protease 20, TLSP, Trypsin-like protease, hK11|
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ELISA. Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
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|Buffer||PBS containing 0.02 % Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (Add 40-50% Glycerol) at-20 °C for longer.|
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