CYP11B1 Products
(Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))
Categories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008].
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Featured CYP11B1 Categories
CYP11B1 Antibodies
High quality antibodies with extensive validation data.
CYP11B1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP11B1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP11B1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7435544
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (p), IF (cc), IHC (fro), IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN750823
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7241108
Quantity
200 μL
Datasheet
Datasheet
Recommended CYP11B1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966230
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955235
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955236
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP11B1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350927
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3090090
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407919
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CYP11B1 products
: "Expression of selected genes involved in steroidogenesis in the course of enucleation-induced rat adrenal regeneration." in: International journal of molecular medicine, Vol. 33, Issue 3, pp. 613-23, (2014) (PubMed).: "Structural insights into aldosterone synthase substrate specificity and targeted inhibition." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 315-24, (2013) (PubMed).
: "Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene." in: The Journal of biological chemistry, Vol. 274, Issue 34, pp. 23963-8, (1999) (PubMed).
: "Membrane topology and cell surface targeting of microsomal epoxide hydrolase. Evidence for multiple topological orientations." in: The Journal of biological chemistry, Vol. 274, Issue 39, pp. 27898-904, (1999) (PubMed).
: "Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants." in: Human molecular genetics, Vol. 3, Issue 3, pp. 421-8, (1994) (PubMed).
Synonyms and alternative names related to CYP11B1
cytochrome P450, family 11, subfamily B, polypeptide 1 (CYP11B1), cytochrome P450 family 11 subfamily B member 1 (CYP11B1), cytochrome P450, family 11, subfamily b, polypeptide 1 (Cyp11b1), cytochrome P450, subfamily XI B, polypeptide 1 (CYP11B1), AA389061, Cp11ba, CPN1, CYP11B, Cyp11b, Cyp11b-1, FHI, P450C11, P450c11, RATCP11BAProtein level used designations for CYP11B1
- cytochrome P450 11B1, mitochondrial
- CYPXIB1
- cytochrome P-450c11
- cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1
- cytochrome P450C11
- cytochrome p450 XIB1
- steroid 11-beta-hydroxylase
- steroid 11-beta-monooxygenase
- steroid-11-beta-hydroxylase
- Cytochrome P450, subfamily XIB, polypeptide 1 (steroid 11-beta-hydroxylase)
- P450(11 beta)-DS
- P450C11
- aldosterone synthase
- cytochrome P450(11 beta)-DS
- cytochrome P450, subfamily 11B, polypeptide 1
- 11-beta-hydroxylase
- 11beta-hydroxylase
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