CYP26B1 Products
(Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))
Categories
This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].
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Featured CYP26B1 Categories
CYP26B1 Antibodies
High quality antibodies with extensive validation data.
CYP26B1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP26B1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (5)
Cat. No.
ABIN185731
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN527926
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF
Validations
- (4)
Cat. No.
ABIN5576339
Quantity
100 μL
Datasheet
Datasheet
Recommended CYP26B1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6214669
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP26B1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350948
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350946
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3091873
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CYP26B1 products
: "Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1." in: The Journal of pharmacology and experimental therapeutics, Vol. 357, Issue 2, pp. 281-92, (2016) (PubMed).: "Expression of a splice variant of CYP26B1 in betel quid-related oral cancer." in: TheScientificWorldJournal, Vol. 2014, pp. 810561, (2014) (PubMed).
: "Cloning and functional studies of a splice variant of CYP26B1 expressed in vascular cells." in: PLoS ONE, Vol. 7, Issue 5, pp. e36839, (2012) (PubMed).
: "Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases." in: Biochemical pharmacology, Vol. 83, Issue 1, pp. 149-63, (2011) (PubMed).
: "CYP26B1 is a novel candidate gene for betel quid-related oral squamous cell carcinoma." in: Oral oncology, Vol. 47, Issue 7, pp. 594-600, (2011) (PubMed).
: "A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation." in: Molecular pharmacology, Vol. 77, Issue 2, pp. 218-27, (2010) (PubMed).
: "The involvement of cytochrome p450 (CYP) 26 in the retinoic acid metabolism of human epidermal keratinocytes." in: Biochimica et biophysica acta, Vol. 1791, Issue 3, pp. 220-8, (2009) (PubMed).
: "Retinoid signaling determines germ cell fate in mice." in: Science (New York, N.Y.), Vol. 312, Issue 5773, pp. 596-600, (2006) (PubMed).
Synonyms and alternative names related to CYP26B1
cytochrome P450 26B1 (CpipJ_CPIJ002537), cytochrome P450 family 26 subfamily B member 1 L homeolog (cyp26b1.L), cytochrome P450 family 26 subfamily B member 1 (CYP26B1), cytochrome P450 family 26 subfamily B member 1 (cyp26b1), cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1), cytochrome P450, family 26, subfamily b, polypeptide 1 (Cyp26b1), cytochrome P450, family 26, subfamily b, polypeptide 1 (cyp26b1), CP26, cyp26a2, CYP26A2, cyp26b1, fc21d03, p450rai-2, P450RAI-2, P450RAI2, RHFCA, wu:fc21d03, wu:fc26h10, zgc:76999Protein level used designations for CYP26B1
- cytochrome P450 26B1
- cytochrome P450, family 26, subfamily B, polypeptide 1
- cytochrome P450 retinoic acid-inactivating 2
- cytochrome P450 retinoid metabolizing protein
- cytochrome P450, subfamily XXVIB, polypeptide 1
- retinoic acid-metabolizing cytochrome
- cytochrome P450, 26, retinoic acid B1
- cytochrome P450RAI-2
- retinoic acid B1
- retinoic acid hydroxylase
- dol
- stocksteif
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