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DACH1 Products

(Dachshund 1 (DACH1))
This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

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Featured DACH1 Categories

DACH1 Antibodies

High quality antibodies with extensive validation data.

DACH1 ELISA Kits

Reliable ELISA kits for a wide range of species.

DACH1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DACH1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7149476
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7236766
Quantity 200 μL
Datasheet Datasheet
Reactivity Bat, Chicken, Hamster, Horse, Human, Monkey, Mouse, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN960126
Quantity 100 μg
Datasheet Datasheet

Recommended DACH1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1129155
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6215795
Quantity 96 tests
Datasheet Datasheet

Recommended DACH1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122598
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351070
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3137391
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DACH1 products

Wen, Jin: "Production of neural stem cells from human pluripotent stem cells." in: Journal of biotechnology, Vol. 188, pp. 122-9, (2015) (PubMed).

Zhou, Shaikh, Neogi, McFarlane, Zhao, Figg, Brighton, Maniero, Teo, Azizan, Brown: "DACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretion." in: Hypertension (Dallas, Tex. : 1979), Vol. 65, Issue 5, pp. 1103-10, (2015) (PubMed).

Wang: "Suppression of DACH1 promotes migration and invasion of colorectal cancer via activating TGF-β-mediated epithelial-mesenchymal transition." in: Biochemical and biophysical research communications, Vol. 460, Issue 2, pp. 314-9, (2015) (PubMed).

Powe, Dhondalay, Lemetre, Allen, Habashy, Ellis, Rees, Ball: "DACH1: its role as a classifier of long term good prognosis in luminal breast cancer." in: PLoS ONE, Vol. 9, Issue 1, pp. e84428, (2014) (PubMed).

Vonlanthen, Okoniewski, Menigatti, Cattaneo, Pellegrini-Ochsner, Haider, Jiricny, Staiano, Buffoli, Marra: "A comprehensive look at transcription factor gene expression changes in colorectal adenomas." in: BMC cancer, Vol. 14, pp. 46, (2014) (PubMed).

Wu, Yang, Wang, Davoli, DAmico, Li, Cveklova, Kozmik, Lisanti, Russell, Cvekl, Pestell: "DACH1 inhibits transforming growth factor-beta signaling through binding Smad4." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 51673-84, (2003) (PubMed).

Synonyms and alternative names related to DACH1

dachshund family transcription factor 1 (DACH1), dachshund 1 (Drosophila) (Dach1), dachshund family transcription factor 1 S homeolog (dach1.S), dachshund family transcription factor 1 (dach1), dachshund homolog 1 (dach1), dachshund homolog 1 (LOC100550020), dachshund family transcription factor 1 (Dach1), AI182278, Dac, DACH, Dach, dach, E130112M23Rik

Protein level used designations for DACH1

  • dachshund homolog 1
  • dachshund homolog 1 (Drosophila)
  • dachshund 1
  • dachshund protein
  • dachshund homolog 1-like
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