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The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.
human growth factor-regulated tyrosine kinase substrate
, protein pp110
, HGF-regulated tyrosine kinase substrate
, SNAP-25-interacting protein Hrs-2
, hepatocyte growth factor-regulated tyrosine kinase substrate
, hepatocyte growth factor regulated tyrosine kinase
, hepatocyte growth factor regulated tyrosine kinase substrate
, hepatocyte growth-factor-regulated substrate
, hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog