FDFT1 Protein (AA 1-283) (His tag)
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- Target See all FDFT1 Proteins
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-283
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FDFT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMEFVKCL GHPEEFYNLV RFRIGGKRKV MPKMDQDSLS SSLKTCYKYL NQTSRSFAAV IQALDGEMRN AVCIFYLVLR ALDTLEDDMT ISVEKKVPLL HNFHSFLYQP DWRFMESKEK DRQVLEDFPT ISLEFRNLAE KYQTVIADIC RRMGIGMAEF LDKHVTSEQE WDKYCHYVAG LVGIGLSRLF SASEFEDPLV GEDTERANSM GLFLQKTNII RDYLEDQQGG REFWPQEVWS RYVKKLGDFA KPENIDLAVQ CLNELITNAL HHIPDVITYL SRLRNQ
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product FDFT1 Protein
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Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 1-417) protein (GST tag)
FDFT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 1-417) protein (Strep Tag)Crystallography grade FDFT1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 1-416) protein (Strep Tag)Crystallography grade FDFT1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) proteinFDFT1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) proteinFDFT1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) protein (Myc-DYKDDDDK Tag)FDFT1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
- Alternative Name
- FDFT1 (FDFT1 Products)
- Synonyms
- FDFT1 Protein, DKFZp459C1712 Protein, SQS Protein, SS Protein, DGPT Protein, ERG9 Protein, fdft1 Protein, farnesyl-diphosphate farnesyltransferase 1 Protein, squalene synthase Protein, farnesyl diphosphate farnesyl transferase 1 Protein, FDFT1 Protein, fdft1 Protein, LOC100560926 Protein, Fdft1 Protein
- Background
- FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Recombinant human FDFT1 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- Molecular Weight
- 35.4 kDa ( 306aa)
- NCBI Accession
- NP_004453
- UniProt
- P37268
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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