Fibulin 5 Protein (FBLN5) (AA 1-448) (GST tag)
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- Target See all Fibulin 5 (FBLN5) Proteins
- Fibulin 5 (FBLN5)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-448
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Origin
- Human
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Source
- Wheat germ
- Purification tag / Conjugate
- This Fibulin 5 protein is labelled with GST tag.
- Application
- Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
- Purpose
- FBLN5 (Human) Recombinant Protein (P01)
- Sequence
- MPGIKRILTV TILALCLPSP GNAQAQCTNG FDLDRQSGQC LDIDECRTIP EACRGDMMCV NQNGGYLCIP RTNPVYRGPY SNPYSTPYSG PYPAAAPPLS APNYPTISRP LICRFGYQMD ESNQCVDVDE CATDSHQCNP TQICINTEGG YTCSCTDGYW LLEGQCLDID ECRYGYCQQL CANVPGSYSC TCNPGFTLNE DGRSCQDVNE CATENPCVQT CVNTYGSFIC RCDPGYELEE DGVHCSDMDE CSFSEFLCQH ECVNQPGTYF CSCPPGYILL DDNRSCQDIN ECEHRNHTCN LQQTCYNLQG GFKCIDPIRC EEPYLRISDN RCMCPAENPG CRDQPFTILY RDMDVVSGRS VPADIFQMQA TTRYPGAYYI FQIKSGNEGR EFYMRQTGPI SATLVMTRPI KGPREIQLDL EMITVNTVIN FRGSSVIRLR IYVSQYPF
- Characteristics
- Human FBLN5 full-length ORF (BAG52073.1, 1 a.a. - 448 a.a.) recombinant protein with GST tag at N-terminal.
- Purification
- in vitro wheat germ expression system
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Fibulin 5 (FBLN5) (AA 24-448) protein (His tag)
Crystallography grade FBLN5 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Fibulin 5 (FBLN5) (AA 24-448) protein (His tag)Crystallography grade FBLN5 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Fibulin 5 (FBLN5) protein (Myc-DYKDDDDK Tag)FBLN5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Fibulin 5 (FBLN5) proteinFBLN5 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Fibulin 5 (FBLN5) proteinFBLN5 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -80 °C
- Storage Comment
- Best use within three months from the date of receipt of this protein.
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- Target
- Fibulin 5 (FBLN5)
- Alternative Name
- FBLN5 (FBLN5 Products)
- Synonyms
- zgc:103575 Protein, FBLN5 Protein, MGC108414 Protein, Fibulin-5 Protein, DKFZp469K0327 Protein, ADCL2 Protein, ARCL1A Protein, ARMD3 Protein, DANCE Protein, EVEC Protein, FIBL-5 Protein, UP50 Protein, A55 Protein, fibulin 5 Protein, fbln5 Protein, FBLN5 Protein, Fbln5 Protein
- Background
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Synonyms: ARMD3,DANCE,EVEC,FIBL-5,FLJ90059,UP50
Gene Description: fibulin 5
Gene Name: FBLN5
Gene Summary: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
GenBank: AK075147.1, BAG52073.1 - Molecular Weight
- 76.6 kDa (theoreatical)
- Gene ID
- 10516
- Pathways
- SARS-CoV-2 Protein Interactome
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