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FPGS Products

(Folylpolyglutamate Synthase (FPGS))
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq, Jul 2008].

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Featured FPGS Categories

FPGS Antibodies

High quality antibodies with extensive validation data.

FPGS ELISA Kits

Reliable ELISA kits for a wide range of species.

FPGS Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FPGS Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (1)
  • (2)
Cat. No. ABIN2789500
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN2437051
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7153018
Quantity 100 μg
Datasheet Datasheet

Recommended FPGS ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966873
Quantity 96 tests
Datasheet Datasheet

Recommended FPGS Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3080254
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134218
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354409
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our FPGS products

Fukuda, Oguri, Kunii, Sone, Uemura, Takakuwa, Maeno, Kanemitsu, Ohkubo, Takemura, Ito, Niimi: "A folylpoly-γ-glutamate synthase single nucleotide polymorphism associated with response to pemetrexed treatment combined with platinum for non-small cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 102, pp. 15-20, (2016) (PubMed).

Synonyms and alternative names related to FPGS

folylpolyglutamate synthase (fpgs), folylpolyglutamate synthase (fpgS), folylpolyglutamate synthase (FPGS), folylpolyglutamate synthase (SCO2614), folylpolyglutamate synthase (fgs), folylpolyglutamate synthase (folC), dihydrofolate synthase (folC), folylpolyglutamate synthase, mitochondrial (CpipJ_CPIJ008043), folylpolyglutamate synthase (Fpgs), folylpolyglutamyl synthetase (Fpgs), AA408187, BA4689, FPGS, fpgS, SCC88.25c, wu:fk49h03, wu:fk51d09, zgc:63807

Protein level used designations for FPGS

  • fk51d09
  • folylpolyglutamate synthase, mitochondrial
  • folylpolyglutamate synthase
  • folylpoly-gamma-glutamate synthetase
  • tetrahydrofolate synthase
  • tetrahydrofolylpolyglutamate synthase
  • Folylpoly-gamma-glutamate synthetase
  • Tetrahydrofolate synthase
  • Tetrahydrofolylpolyglutamate synthase
  • folylpoly-gammaglutamate synthetase
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