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GAB1 Products

(GRB2-Associated Binding Protein 1 (GAB1))

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The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

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Featured GAB1 Categories

GAB1 Antibodies

High quality antibodies with extensive validation data.

Recommended GAB1 Antibodies

Product
Reactivity
Application
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Cat. No.
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Reactivity Human
Application WB, ELISA, ICC, IHC (fro), IHC (p)
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Cat. No. ABIN7439906
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Cat. No. ABIN7372688
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Recommended GAB1 Proteins

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Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity Human
Source Escherichia coli (E. coli)
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Cat. No. ABIN7405990
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Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406029
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Latest Publications for our GAB1 products

Fan, Wong, Marino, Ou, Shen, Wu, Wong, Reiser, Johnson: "Acquired substrate preference for GAB1 protein bestows transforming activity to ERBB2 kinase lung cancer mutants." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16895-904, (2013) (PubMed).

Sun, Yuan, Liu, Shi, Baker, Vuori, Wu, Feng: "Role of Gab1 in UV-induced c-Jun NH2-terminal kinase activation and cell apoptosis." in: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1531-9, (2004) (PubMed).

Synonyms and alternative names related to GAB1

growth factor receptor bound protein 2-associated protein 1 (Gab1), GRB2-associated binding protein 1 (Gab1), GRB2 associated binding protein 1 (GAB1), AA408973, AW107238

Protein level used designations for GAB1

  • GRB2-associated binder 1
  • GRB2-associated-binding protein 1
  • GRB2-associated binding protein 1 long isoform
  • growth factor receptor bound protein 2-associated protein 1
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