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GABRB1 Products

(gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))

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The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008].

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Featured GABRB1 Categories

GABRB1 Antibodies

High quality antibodies with extensive validation data.

GABRB1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GABRB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7241390
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN1742466
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN604919
Quantity 50 μL
Datasheet Datasheet

Recommended GABRB1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6229781
Quantity 96 tests
Datasheet Datasheet

Recommended GABRB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354658
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3080615
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3080614
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GABRB1 products

Hernandez, Kong, Hu, Zhang, Shen, Jackson, Liu, Jiang, Macdonald: "Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome." in: eNeuro, Vol. 4, Issue 1, (2017) (PubMed).

Kerti-Szigeti, Nusser: "Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells." in: eLife, Vol. 5, (2016) (PubMed).

King, Manning, Trimmer: "A unique ion channel clustering domain on the axon initial segment of mammalian neurons." in: The Journal of comparative neurology, Vol. 522, Issue 11, pp. 2594-608, (2014) (PubMed).

Ohkawa, Satake, Yokoi, Miyazaki, Ohshita, Sobue, Takashima, Watanabe, Fukata, Fukata: "Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 24, pp. 8151-63, (2014) (PubMed).

Zhou, Huang, Ding, Deel, Arain, Murray, Patel, Flanagan, Gallagher: "Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome." in: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21458-72, (2013) (PubMed).

Eyre, Renzi, Farrant, Nusser: "Setting the time course of inhibitory synaptic currents by mixing multiple GABA(A) receptor ? subunit isoforms." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 17, pp. 5853-67, (2012) (PubMed).

Gutierrez, Mark, Masseck, Maejima, Kuckelsberg, Hyde, Krause, Kruse, Herlitze: "Optogenetic control of motor coordination by Gi/o protein-coupled vertebrate rhodopsin in cerebellar Purkinje cells." in: The Journal of biological chemistry, Vol. 286, Issue 29, pp. 25848-58, (2011) (PubMed).

Pöltl, Hauer, Fuchs, Tretter, Sieghart: "Subunit composition and quantitative importance of GABA(A) receptor subtypes in the cerebellum of mouse and rat." in: Journal of neurochemistry, Vol. 87, Issue 6, pp. 1444-55, (2004) (PubMed).

Ogris, Pöltl, Hauer, Ernst, Oberto, Wulff, Höger, Wisden, Sieghart: "Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit." in: Biochemical pharmacology, Vol. 68, Issue 8, pp. 1621-9, (2004) (PubMed).

McKernan, Rosahl, Reynolds, Sur, Wafford, Atack, Farrar, Myers, Cook, Ferris, Garrett, Bristow, Marshall, Macaulay, Brown, Howell, Moore, Carling, Street, Castro, Ragan, Dawson, Whiting: "Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype." in: Nature neuroscience, Vol. 3, Issue 6, pp. 587-92, (2000) (PubMed).

Synonyms and alternative names related to GABRB1

gamma-aminobutyric acid type A receptor beta1 subunit (GABRB1), gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), gamma-aminobutyric acid type A receptor beta 1 subunit (Gabrb1), gamma-aminobutyric acid (GABA) A receptor, beta 1 (gabrb1), gamma-aminobutyric acid type A receptor beta1 subunit (Gabrb1), AW061132, B230208N19Rik, Gabrb-1, GARB1, si:dkey-20i10.4

Protein level used designations for GABRB1

  • GABA(A) receptor subunit beta-1
  • GABA(A) receptor, beta 1
  • gamma-aminobutyric acid receptor subunit beta-1
  • Gamma-aminobutyric acid receptor beta 1
  • gamma-aminobutyric acid (GABA) A receptor, beta 1
  • gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1
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