GIT1 Products
(GIT1)
Categories
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine- phosphorylated paxillin in cytoplasmic complexes (By similarity).
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Featured GIT1 Categories
GIT1 Antibodies
High quality antibodies with extensive validation data.
GIT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
GIT1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GIT1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN7267383
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7144546
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS
Validations
- (4)
Cat. No.
ABIN6242999
Quantity
400 μL
Datasheet
Datasheet
Recommended GIT1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1122359
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1122360
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1122361
Quantity
96 tests
Datasheet
Datasheet
Recommended GIT1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3092784
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3135633
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2721889
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our GIT1 products
: "GIT1 regulates angiogenic factor secretion in bone marrow mesenchymal stem cells via NF-κB/Notch signalling to promote angiogenesis." in: Cell proliferation, Vol. 52, Issue 6, pp. e12689, (2019) (PubMed).: "GIT1 contributes to autophagy in osteoclast through disruption of the binding of Beclin1 and Bcl2 under starvation condition." in: Cell death & disease, Vol. 9, Issue 12, pp. 1195, (2018) (PubMed).
: "GPCR kinase 2-interacting protein-1 protects against ischemia-reperfusion injury of the spinal cord by modulating ASK1/JNK/p38 signaling." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, pp. fj201800548, (2018) (PubMed).
: "Interactions between E6, FAK, and GIT1 at paxillin LD4 are necessary for transformation by bovine papillomavirus 1 E6." in: Journal of virology, Vol. 88, Issue 17, pp. 9927-33, (2014) (PubMed).
: "Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium." in: Cardiovascular research, Vol. 104, Issue 1, pp. 103-15, (2014) (PubMed).
: "The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation." in: American journal of physiology. Cell physiology, Vol. 305, Issue 5, pp. C519-28, (2013) (PubMed).
: "GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice." in: Nature medicine, Vol. 17, Issue 5, pp. 566-72, (2011) (PubMed).
: "Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS." in: The Journal of biological chemistry, Vol. 286, Issue 44, pp. 37932-44, (2011) (PubMed).
: "The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 29, pp. 9738-52, (2010) (PubMed).
: "Proteomics analysis of immuno-precipitated synaptic protein complexes." in: Journal of proteomics, Vol. 72, Issue 1, pp. 82-90, (2009) (PubMed).
Synonyms and alternative names related to GIT1
GIT ArfGAP 1 (GIT1), GIT ArfGAP 1 (Git1), G protein-coupled receptor kinase interacting ArfGAP 1 (GIT1), G protein-coupled receptor kinase-interactor 1 (Git1), Cat-1, p95CatProtein level used designations for GIT1
- ARF GAP GIT1
- ARF GTPase-activating protein GIT1
- CAT-1
- CAT1
- G protein-coupled receptor kinase interactor 1
- G protein-coupled receptor kinase-interactor 1
- GRK-interacting protein 1
- cool-associated and tyrosine-phosphorylated protein 1
- G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein (GIT1)
- G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
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