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GRIK2 Products

(Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Categories

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008].

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Featured GRIK2 Categories

GRIK2 Antibodies

High quality antibodies with extensive validation data.

GRIK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

GRIK2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GRIK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN7267415
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, Neut, FACS
Validations
  • (3)
Cat. No. ABIN5611208
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN3022675
Quantity 100 μL
Datasheet Datasheet

Recommended GRIK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN776955
Quantity 96 tests
Datasheet Datasheet
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN774999
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN778939
Quantity 96 tests
Datasheet Datasheet

Recommended GRIK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355738
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418479
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2722000
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our GRIK2 products

Kindt, Sheets: "Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish." in: Frontiers in cell and developmental biology, Vol. 6, pp. 114, (2018) (PubMed).

Funk, Janech, Dillon, Bissler, Siroky, Bell: "Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid." in: Journal of the American Society of Nephrology : JASN, Vol. 25, Issue 6, pp. 1187-97, (2014) (PubMed).

Gut, Beske, Hubbard, Lyman, Hamilton, McNutt: "Novel application of stem cell-derived neurons to evaluate the time- and dose-dependent progression of excitotoxic injury." in: PLoS ONE, Vol. 8, Issue 5, pp. e64423, (2013) (PubMed).

Motazacker, Rost, Hucho, Garshasbi, Kahrizi, Ullmann, Abedini, Nieh, Amini, Goswami, Tzschach, Jensen, Schmitz, Ropers, Najmabadi, Kuss: "A defect in the ionotropic glutamate receptor 6 gene (GRIK2) is associated with autosomal recessive mental retardation." in: American journal of human genetics, Vol. 81, Issue 4, pp. 792-8, (2007) (PubMed).

Pinheiro, Mulle: "Kainate receptors." in: Cell and tissue research, Vol. 326, Issue 2, pp. 457-82, (2006) (PubMed).

Delorme, Krebs, Chabane, Roy, Millet, Mouren-Simeoni, Maier, Bourgeron, Leboyer: "Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder." in: Neuroreport, Vol. 15, Issue 4, pp. 699-702, (2004) (PubMed).

Tanaka: "Functions of glutamate transporters in the brain." in: Neuroscience research, Vol. 37, Issue 1, pp. 15-9, (2000) (PubMed).

Paschen, Blackstone, Huganir, Ross: "Human GluR6 kainate receptor (GRIK2): molecular cloning, expression, polymorphism, and chromosomal assignment." in: Genomics, Vol. 20, Issue 3, pp. 435-40, (1994) (PubMed).

Synonyms and alternative names related to GRIK2

glutamate ionotropic receptor kainate type subunit 2 (GRIK2), glutamate receptor, ionotropic, kainate 2 L homeolog (grik2.L), glutamate receptor, ionotropic, kainate 2 (grik2), glutamate ionotropic receptor kainate type subunit 2 (Grik2), glutamate receptor, ionotropic, kainate 2 (beta 2) (Grik2), AW124492, eaa4, EAA4, glr6, GLR6, GluK2, gluk6, GLUK6, Glur-6, glur6, GluR6, GLUR6, Glur6, Glurbeta2, grik2, GRIK2, grik2-A, GRIK5, mrt6, MRT6

Protein level used designations for GRIK2

  • glutamate receptor 6
  • glutamate receptor, ionotropic kainate 2
  • glutamate receptor, ionotropic, kainate 5
  • bA487F5.1
  • excitatory amino acid receptor 4
  • gluR-6
  • glutamate receptor form A
  • glutamate receptor form B
  • glutamate receptor form C
  • glutamate receptor form D
  • glutamate receptor form E
  • glutamate receptor ionotropic, kainate 2
  • gluR beta-2
  • glutamate receptor beta-2
  • glutamate receptor, ionotropic, kainate 2
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