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HLA-A Proteins

(Major Histocompatibility Complex, Class I, A (HLA-A))
HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008].
HLA-A Protein (AA 24-365) (GST tag) HLA-A Protein (AA 24-365) (GST tag) HLA-A Protein (AA 24-365) (GST tag) (ABIN1306741)

HLA-A Origin: Human Host: Wheat germ Recombinant WB, AP, AA, ELISA

HLA-A Protein (Fc Tag) (ABIN6964124)

HLA-A Origin: Human Host: HEK-293 Cells Recombinant

HLA-A Protein (AA 83-352) (His tag) (ABIN7412848)

HLA-A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

HLA-A Proteins by Origin

Find HLA-A Proteins for a variety of species such as anti-Human HLA-A, anti-Rabbit HLA-A. The species listed below are among those available. Click on a link to go to the corresponding products.

HLA-A Proteins by Source

Here you will find HLA-A Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

HLA-A Proteins by Protein Type

Here you can find HLA-A Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

HLA-A Proteins by Application

Find HLA-A Proteins validated for a specific application such as WB, Imm, PC, SDS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular HLA-A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306741
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN6964124
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7412848
Quantity 100 μg
Datasheet Datasheet
Reactivity Rabbit
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7404614
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1065552
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HLA-A Proteins

Klöß, Chambron, Gardlowski, Arseniev, Koch, Esser, Glienke, Seitz, Köhl: "Increased sMICA and TGFβ1 levels in HNSCC patients impair NKG2D-dependent functionality of activated NK cells." in: Oncoimmunology, Vol. 4, Issue 11, pp. e1055993, (2015) (PubMed).

Aliases for HLA-A Proteins

major histocompatibility complex, class I, A (HLA-A) Proteins
HLAA Proteins
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