Phone:: +1 877 302 8632
Fax:: +1 888 205 9894 (Toll-free)
E-Mail:: orders@antibodies-online.com

For best experience we recommend to activate Javascript in your browser.

Nicotinamide

Inh 98-92-0 Pyridine-3-carboxylic acid amide

/ (Nicotinamide)

1 image

Catalog No. ABIN7233271

Quick Overview for Nicotinamide (ABIN7233271)

Application

Inhibition (Inh)

Chemical Name

Pyridine-3-carboxylic acid amide

Purpose

SIRT1 inhibitor, essential nutrient

Characteristics

Essential nutrient (amide form of Vitamin B3) that is incorporated into cofactors NADH/NAD+, important for ATP production and other key metabolic functions. Transiently inhibits SIRT1/SIRT3 through feedback inhibition (IC50 ~ 50 μM), but is quickly converted to NAD+ in cells. Also inhibits certain kinases (e.g. ROCK and CK1), making it a regulator of hPSC pluripotency, survival, and differentiation. Inhibits differentiation and enhances functionality of hematopoietic stem/progenitor cells (HSPCs).

Purity

>99 %

Formula

C6H6N2O

Solubility

Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml)
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

5-Azacytidine
Inh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

SAHA (Vorinostat)
Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid

Phenylbutyrate Na
Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

CI-994
Inh 112522-64-2 4-(Acetylamino)-N-(2-aminophenyl)benzamide

Tranylcypromine hemisulfate (±)
Inh Cell-permeable 13492-01-8 Trans (±)-2-phenylcyclopropanamine, hemisulfate salt

Tenovin-1
Inh 380315-80-0 N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide

HPA (Hexyl-4-pentynoic acid)
Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)

Restrictions

For Research Use only
Format

Powder

Storage

RT
Background

Nicotinic acid amide, Niacinamide, Vitamin B3, NAM,Epigenetics,DNA damage,Protein deacetylase,Kinase,Stem cells,Cancer,NAD, NADP pathways,Posttranslational modification

Molecular Weight

122.1

CAS-No

98-92-0

You are here: