ITPR1 Products
(Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
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This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009].
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Featured ITPR1 Categories
ITPR1 Antibodies
High quality antibodies with extensive validation data.
ITPR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ITPR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (6)
Cat. No.
ABIN3043862
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7156293
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Human, Mouse, Rat
Application
IHC, WB
Validations
- (1)
- (3)
Cat. No.
ABIN1742253
Quantity
200 μL
Datasheet
Datasheet
Recommended ITPR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1308255
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3082063
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3082064
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ITPR1 products
: "Inositol 1,4,5-triphosphate receptor is selectively expressed in cerebellum but not cerebellum-like structures of the elasmobranch fish, Leucoraja erinacea." in: Heliyon, Vol. 5, Issue 1, pp. e01176, (2019) (PubMed).: "BAP1 regulates IP3R3-mediated Ca(2+) flux to mitochondria suppressing cell transformation. ..." in: Nature, Vol. 546, Issue 7659, pp. 549-553, (2017) (PubMed).
: "Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta." in: PLoS genetics, Vol. 12, Issue 7, pp. e1006156, (2016) (PubMed).
: "Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells." in: Science signaling, Vol. 7, Issue 345, pp. ra93, (2014) (PubMed).
: "Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain." in: Proteomics, Vol. 14, Issue 2-3, pp. 241-61, (2014) (PubMed).
: "Divergent signaling mechanisms for venous versus arterial contraction as revealed by endothelin-1." in: Journal of vascular surgery, (2014) (PubMed).
: "Abolished InsP3R2 function inhibits sweat secretion in both humans and mice." in: The Journal of clinical investigation, Vol. 124, Issue 11, pp. 4773-80, (2014) (PubMed).
: "Microdomains of muscarinic acetylcholine and Ins(1,4,5)P? receptors create 'Ins(1,4,5)P? junctions' and sites of Ca²+ wave initiation in smooth muscle." in: Journal of cell science, Vol. 125, Issue Pt 22, pp. 5315-28, (2013) (PubMed).
: "Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels." in: The Journal of biological chemistry, Vol. 288, Issue 16, pp. 11122-34, (2013) (PubMed).
: "Proteomic analysis of primary cultured rat cortical neurons in chemical ischemia." in: Neurochemical research, Vol. 38, Issue 8, pp. 1648-60, (2013) (PubMed).
Synonyms and alternative names related to ITPR1
inositol 1,4,5-trisphosphate receptor type 1 (ITPR1), inositol 1,4,5-trisphosphate receptor 1 (Itpr1), inositol 1,4,5-trisphosphate receptor, type 1 (Itpr1), D6Pas2, ENSMUSG00000072853, Gm10429, I145TR, InsP3R, InsP3R1, INSP3R1, Ip3r, IP3R, IP3R1, Itpr-1, opt, P400, Pcp-1, Pcp1, SCA15, SCA16, SCA29Protein level used designations for ITPR1
- inositol 1,4,5-triphosphate receptor, type 1
- type I inositol triphosphate receptor
- IP3 receptor
- IP3R 1
- InsP3R type I
- InsP>3
- Purkinje cell protein 1
- inositol 1,4,5-triphosphate receptor 1
- inositol 1,4,5-trisphosphate receptor type 1
- inositol 1,4,5-trisphosphate-binding protein P400
- insP3R1
- opisthotonus
- protein PCD-6
- type 1 InsP3 receptor
- type 1 inositol 1,4,5-trisphosphate receptor
- IP-3-R
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