anti-Rat (Rattus) IL-6 Receptor antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended IL-6 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin-6 Receptor (IL6R) Antibodies
  • IL6R
  • il-6ra
  • CD126
  • IL-6R-1
  • IL-6RA
  • IL6Q
  • IL6RA
  • IL6RQ
  • gp80
  • IL6R1
  • Il6ra
  • IL-6Ralpha
  • IL-6R
  • Il6r
  • interleukin 6 receptor
  • interleukin 6 receptor, alpha
  • IL6R
  • il6r
  • Il6r
  • Il6ra
Epitope
AA 386-430
24
19
17
14
10
7
7
6
6
6
5
5
5
5
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
185
86
44
1
Host
Rabbit
131
93
45
21
1
1
1
Clonality
Polyclonal
Conjugate
This IL-6 Receptor antibody is un-conjugated
26
15
15
15
9
8
6
6
4
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
131
121
104
69
40
24
24
17
14
12
10
9
9
8
8
6
4
3
2
2
2
2
2
1
Options
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Catalog No. ABIN734693
$ 318.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN734702 IHC (p) WB HRP Rabbit IgG AA 386-430 Log in to see Polyclonal 0
1 ABIN734695 IHC (p) WB Biotin Rabbit IgG AA 386-430 Log in to see Polyclonal 0
1 ABIN4325585 ELISA ICC IF IHC (fro) IHC (p) WB Rabbit IgG AA 19-108 Log in to see Polyclonal 0

General

Antigen Interleukin-6 Receptor (IL6R) Antibodies
Epitope AA 386-430
(24), (19), (17), (14), (10), (7), (7), (6), (6), (6), (5), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine), Rat (Rattus)
(185), (86), (44), (1)
Host Rabbit
(131), (93), (45), (21), (1), (1), (1)
Clonality
Polyclonal
Conjugate This IL-6 Receptor antibody is un-conjugated
(26), (15), (15), (15), (9), (8), (6), (6), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(131), (121), (104), (69), (40), (24), (24), (17), (14), (12), (10), (9), (9), (8), (8), (6), (4), (3), (2), (2), (2), (2), (2), (1)
Pubmed 2 references available
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Product Details anti-IL-6 Receptor Antibody

Target Details IL-6 Receptor Application Details Handling References for anti-IL-6 Receptor antibody (ABIN734693) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse IL-6R alpha
Isotype IgG

Target Details IL-6 Receptor

Product Details anti-IL-6 Receptor Antibody Application Details Handling References for anti-IL-6 Receptor antibody (ABIN734693) Images back to top
Antigen
Alternative Name IL-6R alpha (IL6R Antibody Abstract)
Background

Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.

Subcellular location: Cytoplasm

Synonyms: Il6r, CD126, IL-6R, Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Il6ra

Gene ID 16194
UniProt P22272
Pathways JAK-STAT Signaling, Autophagy, Growth Factor Binding

Application Details

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Handling References for anti-IL-6 Receptor antibody (ABIN734693) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details References for anti-IL-6 Receptor antibody (ABIN734693) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-IL-6 Receptor antibody (ABIN734693)

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling Images back to top
Product cited in:

Urushima, Fujimoto, Mishima, Ohkawara, Honda, Lee, Kawahata, Serada, Naka: "Leucine-rich alpha 2 glycoprotein promotes Th17 differentiation and collagen-induced arthritis in mice through enhancement of TGF-β-Smad2 signaling in naïve helper T cells." in: Arthritis research & therapy, Vol. 19, Issue 1, pp. 137, 2017 Method employed by authors: Immunohistochemistry (IHC), Immunohistochemistry (IHC) (Sample species: Mouse (Murine)).

Prystaz, Kaiser, Kovtun, Haffner-Luntzer, Fischer, Rapp, Liedert, Strauss, Waetzig, Rose-John, Ignatius: "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing." in: The American journal of pathology, Vol. 188, Issue 2, pp. 474-490, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)). Further details: Sample: bone

Images

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Handling References for anti-IL-6 Receptor antibody (ABIN734693) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Interleukin-6 Receptor (IL6R) (AA 386-430) antibody (ABIN734693) Formalin-fixed and paraffin embedded human endometrial carcinoma labeled with Anti IL...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Interleukin-6 Receptor (IL6R) (AA 386-430) antibody (ABIN734693) Paraformaldehyde-fixed, paraffin embedded Mouse brain Antigen retrieval by boiling in...