anti-Human IL2 Receptor beta antibody for Neutralization

Recommended IL2 Receptor beta Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, beta (IL2RB) Antibodies
  • IL2RB
  • il-2rb
  • CD122
  • IL15RB
  • P70-75
  • IL2RBC
  • IL-15Rbeta
  • IL15Rbeta
  • Il-2/15Rbeta
  • Il-2Rbeta
  • p70
  • interleukin 2 receptor subunit beta
  • interleukin-2 receptor subunit beta
  • interleukin 2 receptor, beta
  • interleukin 2 receptor, beta chain
  • IL2RB
  • LOC510185
  • il2rb
  • Il2rb
Epitope
AA 27-239
35
16
16
8
7
7
6
4
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
226
190
97
29
10
1
1
Host
Mouse
145
135
91
Clonality
Monoclonal
Conjugate
This IL2 Receptor beta antibody is un-conjugated
31
30
22
15
9
8
6
6
6
6
6
5
4
4
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut)
217
131
66
63
43
26
15
14
13
10
9
4
3
3
2
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN4900009
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1983280 Neut IHC WB Mouse IgG1 AA 27-239 Log in to see MM0392-1Y60 0

General

Antigen Interleukin 2 Receptor, beta (IL2RB) Antibodies
Epitope AA 27-239
(35), (16), (16), (8), (7), (7), (6), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(226), (190), (97), (29), (10), (1), (1)
Host Mouse
(145), (135), (91)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2 Receptor beta antibody is un-conjugated
(31), (30), (22), (15), (9), (8), (6), (6), (6), (6), (6), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut)
(217), (131), (66), (63), (43), (26), (15), (14), (13), (10), (9), (4), (3), (3), (2), (1), (1), (1), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-IL2 Receptor beta Antibody

Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta antibody (ABIN4900009) Images
Specificity Detects human IL-2 R beta in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rh gamma c, rhIL-4 R, or rhIL-6 R is observed.
Purification Protein A or G purified from ascites
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-2 R beta , Ala27-Asp239, Accession # NP_000869
Clone 27302
Isotype IgG1
Plasmids, Primers & others

Target Details IL2 Receptor beta

Product Details anti-IL2 Receptor beta Antibody Application Details Handling References for anti-IL2 Receptor beta antibody (ABIN4900009) Images back to top
Antigen
Alternative Name IL-2 R beta (IL2RB Antibody Abstract)
Background Alternative Names: CD122, CD122 antigen, high affinity IL-2 receptor beta subunit, High affinity IL-2 receptor subunit beta, IL-15 R beta, IL-2 receptor subunit beta, IL2R beta, IL-2R subunit beta, IL2RB, IL-2RB, interleukin 15 receptor, beta, interleukin 2 receptor, beta, interleukin-2 receptor subunit beta, P70-75, p75
Gene ID 3560
NCBI Accession NP_000869
Pathways JAK-STAT Signaling, Growth Factor Binding

Application Details

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Handling References for anti-IL2 Receptor beta antibody (ABIN4900009) Images back to top
Application Notes Flow Cytometry 2.5 μg/10^6 cells
Immunohistochemistry 8-25 μg/mL
Neutralization 0.05-0.15 μg/mL
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details References for anti-IL2 Receptor beta antibody (ABIN4900009) Images back to top
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-IL2 Receptor beta antibody (ABIN4900009)

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling Images back to top
Product cited in:

Jiang, Chen, An, Yang, Zhang, Cheng: "Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling." in: Scientific reports, Vol. 6, pp. 32320, 2016 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ndhlovu, Leal, Eccles-James, Jha, Lanteri, Norris, Barbour, Wachter, Andersson, Taskén, Torheim, Aandahl, Kallas, Nixon: "A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties." in: European journal of immunology, Vol. 40, Issue 1, pp. 134-41, 2010 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Rose, Lambotte, Pallier, Delfraissy, Colle: "Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7389-97, 2009 Method employed by authors: ELISA (ELISA) (Sample species: Human).

Eberly, Kader, Hassan, Rogers, Zhou, Mueller, Mattapallil, Piatak, Lifson, Katsikis, Roederer, Villinger, Mattapallil: "Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1439-48, 2009 Method employed by authors: Flow Cytometry (FACS) (Sample species: Rhesus Monkey).

Miranda-Carús, Balsa, Benito-Miguel, Pérez de Ayala, Martín-Mola: "IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 2, pp. 1463-76, 2004 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Images

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta antibody (ABIN4900009) back to top
Supplier Images
Neutralization (Neut) image for anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) antibody (ABIN4900009) Cell Proliferation Induced by IL-2 and Neutralization by Human IL-2 R beta Antibody. ...
Immunohistochemistry (IHC) image for anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) antibody (ABIN4900009) IL-2 R beta in Human Lymph Node. IL-2 R beta was detected in immersion fixed frozen s...