Leptin Proteins
(Leptin (LEP))
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008].
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67 results :
LEP
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LEP
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
>95 % as determined by reducing SDS-PAGE.
1 image
LEP
Origin: Goldfish
Host: Yeast
Recombinant
> 95 % as determined by reducing SDS-PAGE.
1 image
LEP
Origin: Human
Host: Mammalian Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
LEP
Origin: Pig
Host: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
LEP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
LEP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by SDS-PAGE
WB, ELISA
1 image
LEP
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
Rockland 012-001-320-0200
LEP
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
95,00%
SDS
Rockland Original
LEP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
90 %
ELISA
1 image
4 references
Rockland 012-001-320-1000
LEP
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
Rockland Original
LEP
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
LEP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
LEP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
LEP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
LEP
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 97 % by SDS-PAGE.
Active
LEP
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
LEP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
LEP
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
LEP
Origin: Chicken
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
Latest Publications for our Leptin Proteins
: "The effects of adipokines on cartilage and meniscus catabolism." in: Connective tissue research, Vol. 52, Issue 6, pp. 523-33, (2012) (PubMed).: "Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues: in vitro and ex vivo studies in humans." in: Diabetes Care, Vol. 34, Issue 1, pp. 132-8, (2011) (PubMed).
: "Effects of orexigenic peptides and leptin on melatonin secretion during different photoperiods in seasonal breeding ewes: an in vitro study." in: Domestic animal endocrinology, Vol. 40, Issue 3, pp. 139-46, (2011) (PubMed).
: "Effect of bupivacaine on sevoflurane-induced preconditioning in isolated rat hearts." in: European journal of pharmacology, Vol. 647, Issue 1-3, pp. 132-8, (2010) (PubMed).
: "Seasonal effects of central leptin infusion and prolactin treatment on pituitary SOCS-3 gene expression in ewes." in: The Journal of endocrinology, Vol. 208, Issue 1, pp. 81-8, (2010) (PubMed).
: "The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system." in: Endocrinology, Vol. 150, Issue 11, pp. 5016-26, (2009) (PubMed).
: "Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats." in: Diabetes, Vol. 55, Issue 9, pp. 2602-10, (2006) (PubMed).
: "Leptin concentrations in maternal serum and amniotic fluid during the second trimenon: differential relation to fetal gender and maternal morphometry." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 86, Issue 2, pp. 151-7, (1999) (PubMed).
: "Genomic structure and promoter analysis of the human obese gene." in: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 3971-4, (1996) (PubMed).
: "Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue." in: Diabetes, Vol. 44, Issue 7, pp. 855-8, (1995) (PubMed).
Aliases for Leptin Proteins
leptin (Lep) Proteinsleptin (LEP) Proteins
leptin (lep) Proteins
LEPD Proteins
ob Proteins
OB Proteins
obese Proteins
OBS Proteins
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