KAT6B Products
(K(lysine) Acetyltransferase 6B (KAT6B))
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The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].
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KAT6B Antibodies
High quality antibodies with extensive validation data.
Recommended KAT6B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (3)
Cat. No.
ABIN7193390
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6263496
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF, IHC (p)
Validations
- (2)
Cat. No.
ABIN5584147
Quantity
100 μL
Datasheet
Datasheet
Recommended KAT6B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311874
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our KAT6B products
: "Investigation of MYST4 histone acetyltransferase and its involvement in mammalian gametogenesis." in: BMC developmental biology, Vol. 7, pp. 123, (2008) (PubMed).: "The role of the MORF/MRG family of genes in cell growth, differentiation, DNA repair, and thereby aging." in: Annals of the New York Academy of Sciences, Vol. 1100, pp. 299-305, (2007) (PubMed).
: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).
: "Human interleukin-5 expression is synergistically regulated by histone acetyltransferase CBP/p300 and transcription factors C/EBP, NF-AT and AP-1." in: Cytokine, Vol. 27, Issue 4-5, pp. 93-100, (2004) (PubMed).
: "The MYST family of histone acetyltransferases." in: Current topics in microbiology and immunology, Vol. 274, pp. 203-36, (2003) (PubMed).
Synonyms and alternative names related to KAT6B
K(lysine) acetyltransferase 6B (kat6b), lysine acetyltransferase 6B (KAT6B), K(lysine) acetyltransferase 6B (Kat6b), AI507552, B130044K16Rik, GTPTS, id:ibd5103, mKIAA0383, MORF, Morf, MOZ2, MYST-4, MYST4, Myst4, qkf, querkopf, si:dkey-24f15.3, ZC2HC6BProtein level used designations for KAT6B
- histone acetyltransferase MYST4
- MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4
- MOZ-related factor
- MYST histone acetyltransferase (monocytic leukemia) 4
- MYST-4
- histone acetyltransferase KAT6B
- histone acetyltransferase MORF
- histone acetyltransferase MOZ2
- monocytic leukemia zinc finger protein-related factor
- MYST histone acetyltransferase monocytic leukemia 4
- histone acetyltransferase querkopf
- monocytic leukemia
- protein querkopf
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