BMP2 ELISA Kit

Catalog No. ABIN2042362

Product Details BMP2 ELISA Kit

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reactivity: Rat

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 62.5-4000 pg/mL

Minimum Detection Limit: 62.5 pg/mL

Application: ELISA

Brand: BioAssay™

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivity: < 2 pg/mL

Components: 96-well plate pre-coated with anti-BMP-2, Rat
Lyophilized recombinant BMP-2, Rat standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Application Details

Plate: Pre-coated

Protocol: Sandwich ELISA quantitative detection kit for Rat BMP-2 in bone tissue, cell culture supernates and serum.Bone morphogenetic protein-2 (BMP-2, BMP 2A) belongs to the transforming growth factor beta (TGF- ) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase (MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins (BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant rat BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26kD.

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

Target Details for BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Alternative Name: BMP-2 (BMP2 Products)

Synonyms: BDA2 ELISA Kit, BMP2A ELISA Kit, AI467020 ELISA Kit, Bmp2a ELISA Kit, BMP-2 ELISA Kit, xBMP-2 ELISA Kit, xbmp2 ELISA Kit, BMP2 ELISA Kit, bmp2a ELISA Kit, bmp2 ELISA Kit, wu:fc59d09 ELISA Kit, bone morphogenetic protein 2 ELISA Kit, bone morphogenetic protein 2 L homeolog ELISA Kit, Bone morphogenetic protein 2 ELISA Kit, bone morphogenetic protein 2a ELISA Kit, BMP2 ELISA Kit, Bmp2 ELISA Kit, bmp2.L ELISA Kit, bmp2 ELISA Kit, bmp2a ELISA Kit

Gene ID: 29373

UniProt: P49001

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation