IL-6 ELISA Kit

Catalog No. ABIN2690566

Mouse IL-6 ELISA Kit, Colorimetric assay for quantification of Mouse IL-6, that has been mentioned in 3+ publications.

Quick Overview for IL-6 ELISA Kit (ABIN2690566)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivity: Mouse

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Sample Type: Serum, Plasma, Cell Culture Supernatant

Product Details IL-6 ELISA Kit

Purpose: The Mouse IL-6 ELISA Kit is for the quantitative determination of mouse IL-6 in serum, plasma, and cell culture supernatant.

Analytical Method: Quantitative

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

BD OptEIA™ Mouse IL-6 ELISA Kit

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C

Storage Comment: 1. Store unopened kit at 2 - 8°C. Do not use kit after expiration date.
2. Before use, bring all reagents to room temperature (18 - 25°C). Immediately after use, return to proper storage conditions.
3. Lyophilized standards are stable until kit expiration date. After reconstitution, use freshly reconstituted standard within 12 hours (stored at 2 - 8°C).

References for IL-6 ELISA Kit (ABIN2690566)

Van Snick: "Interleukin-6: an overview." in: Annual review of immunology, Vol. 8, pp. 253-78, (1990) (PubMed).

Van Snick, Cayphas, Szikora, Renauld, Van Roost, Boon, Simpson: "cDNA cloning of murine interleukin-HP1: homology with human interleukin 6." in: European journal of immunology, Vol. 18, Issue 2, pp. 193-7, (1988) (PubMed).

Van Snick, Cayphas, Vink, Uyttenhove, Coulie, Rubira, Simpson: "Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 24, pp. 9679-83, (1987) (PubMed).

Target Details for IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Alternative Name: IL-6

Background: Interleukin-6 (IL-6)1-4 is a multifunctional cytokine which regulates immune responses, acute-phase reactions and hematopoiesis. It has also been called IFN-β2, BSF-2, and HPGF. Reported cellular targets for IL-6 action are: hepatocytes, B and T lymphocytes, neurons, tumor cells and multi-potent hematopoietic cells. Mouse IL-6 is a 21.7 kD protein containing 187 amino acid residues.

Pathways: TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome