Anti-Oxidized Low Density Lipoprotein Antibody ELISA Kit
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- Target
- Anti-Oxidized Low Density Lipoprotein Antibody
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Reactivity
- Human
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Detection Range
- 37-1200 mU/mL
- Minimum Detection Limit
- 37 mU/mL
- Application
- ELISA
- Purpose
- Enzyme Immunoassay For The Quantitative Determination Of Human IgG Autoantibodies Against Oxidised Low Density Lipoprotein In Serum
- Sample Type
- Serum
- Analytical Method
- Quantitative
- Specificity
- Antibodies against oxLDL,Anti oxidized LDL autoantibodies
- Components
- plate, assay buffer, wash buffer, standards, cotnrols, conjugate, substrate, stop solution
- Material not included
- pipettes, tubes, reader
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- Sample Volume
- 20 μL
- Plate
- Pre-coated
- Protocol
- Oxidized low density lipoprotein (oLDL) is believed to play a critical role in the development and progression of atherosclerosis. Accumulation of oLDL in macrophages and smooth muscle cells causes foam cell formation, an initial step in the disease. Autoantibodies against oxidatively modified LDL can be used as a parameter that consistently mirrors the occurrence of oxidation processes taking place in vivo. In fact, elevated levels of autoantibodies against oLDL have been detected in the blood stream of patients with coronary artery disease. Moreover, recent studies indicate a correlation between autoantibodies against oLDL and the progression of carotid atherosclerosis. Increased serum concentrations of oLAB have also been described in various diseases such as pre-eclampsia and systemic lupus erythematosus. Decreased oLAB titers were observed during septicemia and myocardial infarction.
- Assay Precision
- Intra-assay (n=8) ≤ 4%, Inter-assay (n=5) ≤ 8%
- Restrictions
- For Research Use only
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- Buffer
- ≤ 0.1 % Proclin
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- Anti-Oxidized Low Density Lipoprotein Antibody
- Alternative Name
- anti-oxLDL antibody
- Target Type
- Antibody
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