NTRK3 ELISA Kit

Catalog No. ABIN5692236

Product Details NTRK3 ELISA Kit

Target: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Binding Specificity: AA 32-429

Reactivity: Rat

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 156 pg/mL - 10000 pg/mL

Minimum Detection Limit: 156 pg/mL

Application: ELISA

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat TRKC. 96wells/kit, with removable strips.

Brand: PicoKine™

Sample Type: Cell Culture Supernatant, Cell Lysate

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO, Immunogen sequence: C32-T429

Sensitivity: < 10 pg/mL

Components: 96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
Adhesive cover

Application Details

Assay Time: 25 min

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

References for NTRK3 ELISA Kit (ABIN5692236)

Chung, Chung, Lee, Chung, Yang, Lee, Choi, Chang, Kim, Suh, Lee, Hwang, Do, Kim: "Expression of neurotrophic factors in injured spinal cord after transplantation of human-umbilical cord blood stem cells in rats." in: Journal of veterinary science, Vol. 17, Issue 1, pp. 97-102, (2016) (PubMed).

Cotter, Johnson, Young, Lin, Rowe: "Competitive effects of long-chain-triglyceride emulsion on the metabolism of medium-chain-triglyceride emulsions." in: The American journal of clinical nutrition, Vol. 50, Issue 4, pp. 794-800, (1989) (PubMed).

Target Details for NTRK3

Target: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Alternative Name: Ntrk3 (NTRK3 Products)

Synonyms: TRKC ELISA Kit, gp145(trkC) ELISA Kit, trkC ELISA Kit, AW125844 ELISA Kit, Ntrk3_tv3 ELISA Kit, TrkC ELISA Kit, neurotrophic receptor tyrosine kinase 3 ELISA Kit, neurotrophic tyrosine kinase, receptor, type 3 ELISA Kit, NTRK3 ELISA Kit, Ntrk3 ELISA Kit

Background:

Synonyms: NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, Ntrk3, Trkc

Tissue Specificity: Widely expressed, mainly in the nervous tissue.

Background: NTRK3 (Neurotrophic Tyrosine Kinase Receptor Type 3), also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. By PCR analysis of a somatic cell hybrid panel and by fluorescence in situ hybridization with the cDNA clone, it mapped the NTRK3 gene to 15q24-q25. TRKC, a member of the TRK family of tyrosine protein kinase genes. They found that TRKC is preferentially expressed in the brain, in situ hybridization studies showed transcripts in the hippocampus, cerebral cortex, and the granular cell layer of the cerebellum. By functional studies in HeLa cells, 5 miRNAs regulate the truncated form of NTRK3.

Cellular Localisation: Membrane, Single-pass type I membrane protein.

UniProt: Q03351

Pathways: RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size