LAT3 Products
(Large Neutral Amino Acid Transporter 3 (LAT3))
Categories
Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
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Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648143
Quantity
96 tests
Datasheet
Datasheet
Synonyms and alternative names related to LAT3
solute carrier family 7 member 6 (SLC7A6), LAT-2, LAT3, y+LAT-2Protein level used designations for LAT3
- Y+L amino acid transporter 2
- amino acid permease
- cationic amino acid transporter, y+ system
- solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
- solute carrier family 7 member 6
- y(+)L-type amino acid transporter 2
- y+LAT2
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