anti-Dog (Canine) BCL2 antibody for Immunofluorescence

Recommended BCL2 Antibody (supplied by: Log in to see )

Antigen
B-Cell CLL/lymphoma 2 (BCL2) Antibodies
  • Bcl-2
  • PPP1R50
  • bcl-2
  • AW986256
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • BCL-2
  • Bcl2
  • BCL2, apoptosis regulator
  • B cell leukemia/lymphoma 2
  • B-cell CLL/lymphoma 2a
  • B-cell CLL/lymphoma 2 protein
  • BCL2
  • Bcl2
  • bcl2a
  • BCL-2
Epitope
AA 41-54
247
78
64
61
40
28
28
26
22
21
16
15
15
15
11
11
9
9
9
9
8
7
7
7
7
6
5
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chimpanzee, Dog (Canine), Human, Monkey, Pig (Porcine)
1257
273
251
69
35
21
20
19
6
3
3
3
3
2
2
Host
Mouse
701
633
19
6
2
Clonality
Monoclonal
Conjugate
This BCL2 antibody is un-conjugated
62
57
53
50
43
25
24
24
23
15
14
14
14
14
14
14
13
13
11
11
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
6
6
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
1028
473
472
423
409
405
223
188
156
155
81
42
33
15
13
9
6
3
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2738523
$ 595.83
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2738524 ELISA FACS IF IHC IHC (p) IP WB Mouse IgG1, kappa AA 41-54 Log in to see 124 0
1 ABIN2738525 FACS IF IHC IHC (p) IP WB Mouse IgG1, kappa AA 41-54 Log in to see 100-D5-124 0
1 ABIN2738522 ELISA FACS IF IHC IHC (p) IP WB Mouse IgG1, kappa Log in to see 100-D5 0
1 ABIN264903 IF IP WB Sheep IgG Log in to see Polyclonal 0
1 ABIN305981 IF IP WB Sheep Log in to see Polyclonal 0
1 ABIN4369850 IF IP WB Sheep Log in to see Polyclonal 0

General

Antigen B-Cell CLL/lymphoma 2 (BCL2) Antibodies
Epitope AA 41-54
(247), (78), (64), (61), (40), (28), (28), (26), (22), (21), (16), (15), (15), (15), (11), (11), (9), (9), (9), (9), (8), (7), (7), (7), (7), (6), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chimpanzee, Dog (Canine), Human, Monkey, Pig (Porcine)
(1257), (273), (251), (69), (35), (21), (20), (19), (6), (3), (3), (3), (3), (2), (2)
Host Mouse
(701), (633), (19), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BCL2 antibody is un-conjugated
(62), (57), (53), (50), (43), (25), (24), (24), (23), (15), (14), (14), (14), (14), (14), (14), (13), (13), (11), (11), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(1028), (473), (472), (423), (409), (405), (223), (188), (156), (155), (81), (42), (33), (15), (13), (9), (6), (3), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-BCL2 Antibody

Target Details BCL2 Application Details Handling Images
Specificity Human BCL2 / Bcl-2
No Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Protein G purified
Immunogen A synthetic peptide, aa41-54 (GaaPAPGIFSSQPG-Cys) of human Bcl-2 protein. Percent identity by BLAST analysis: Human, Chimpanzee, Cat, Pig, Dog (100%), Gorilla, Orangutan, Bovine, Goat (91%), Galago (82%).

Type of Immunogen: Synthetic peptide
Clone 8C8
Isotype IgG1, kappa
Plasmids, Primers & others

Target Details BCL2

Product Details anti-BCL2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name BCL2 / Bcl-2 (BCL2 Antibody Abstract)
Background Name/Gene ID: BCL2
Family: Apoptosis

Synonyms: BCL2, Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50
Gene ID 596
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product Details anti-BCL2 Antibody Target Details BCL2 Handling Images back to top
Application Notes Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: This antibody recognizes a protein of 25-26  kDa, identified as the Bcl-2 alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative. ELISA: Order BSA-free format for coating.
Comment

Target Species of Antibody: Human

Restrictions For Research Use only

Handling

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2°C to 8°C.