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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN2755634 | IC IF IP IHC WB | Rabbit | pSer100, pSer73 | Log in to see | Polyclonal | 0 | |||
1 | ABIN601036 | IF IHC WB | Rabbit | IgG | pSer243 | Log in to see | Polyclonal | 0 | ||
1 | ABIN601038 | IF IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 |
General |
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Antigen | Jun Proto-Oncogene (JUN) Antibodies |
Epitope | pSer73 Alternatives |
Reactivity | Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This C-JUN antibody is un-conjugated Alternatives |
Application |
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
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1 reference available |
Supplier | Log in to see |
Product Details anti-C-JUN AntibodyTarget Details C-JUN Application Details Handling References for anti-C-JUN antibody (ABIN6255488) Images |
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Specificity | Phospho-c-Jun (Ser73) Antibody detects endogenous levels of c-Jun only when phosphorylated at Serine 73 |
Cross-Reactivity | Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio) |
Purification | The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
Immunogen | A synthesized peptide derived from human c-Jun around the phosphorylation site of Serine 73 |
Isotype | IgG |
Plasmids, Primers & others | |
Target Details C-JUNProduct Details anti-C-JUN Antibody Application Details Handling References for anti-C-JUN antibody (ABIN6255488) Images back to top |
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Antigen | |
Alternative Name | c-Jun (JUN Antibody Abstract) |
Background |
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Gene: JUN |
Molecular Weight | 37kDa |
Gene ID | 3725 |
UniProt | P05412, P17535 |
Pathways | MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor |
Application DetailsProduct Details anti-C-JUN Antibody Target Details C-JUN Handling References for anti-C-JUN antibody (ABIN6255488) Images back to top |
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Application Notes | WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500 |
Restrictions | For Research Use only |
HandlingProduct Details anti-C-JUN Antibody Target Details C-JUN Application Details References for anti-C-JUN antibody (ABIN6255488) Images back to top |
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Format | Liquid |
Concentration | 1 mg/mL |
Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | -20 °C |
Storage Comment | Store at -20 °C.Stable for 12 months from date of receipt |
Expiry Date | 12 months |
References for anti-C-JUN antibody (ABIN6255488)Product Details anti-C-JUN Antibody Target Details C-JUN Application Details Handling Images back to top |
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Product cited in: |
Wu, Wang, Fang, Huang, Sun, Xiao, Yan: "MFAP5 promotes tumor progression and bone metastasis by regulating ERK/MMP signaling pathways in breast cancer." in: Biochemical and biophysical research communications, Vol. 498, Issue 3, pp. 495-501, 2018 |
ImagesProduct Details anti-C-JUN Antibody Target Details C-JUN Application Details Handling References for anti-C-JUN antibody (ABIN6255488) back to top |
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Supplier Images |
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